go_id,ontology,go_term,term_definition,evidence GO:0001948,MF,"glycoprotein binding","Interacting selectively and non-covalently with a glycoprotein, a protein that contains covalently bound glycose (monosaccharide) residues. These also include proteoglycans.",IEA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA GO:0007155,BP,"cell adhesion","The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.",IEA GO:0007229,BP,"integrin-mediated signaling pathway","A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.",NAS GO:0008305,CC,"integrin complex","A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.",TAS GO:0009986,CC,"cell surface","The external part of the cell wall and/or plasma membrane.",IDA GO:0010668,BP,"ectodermal cell differentiation","The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.",IEP GO:0030198,BP,"extracellular matrix organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.",IEA GO:0034142,BP,"toll-like receptor 4 signaling pathway","Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.",TAS GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA GO:0046982,MF,"protein heterodimerization activity","Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.",IPI GO:0050900,BP,"leukocyte migration","The movement of a leukocyte within or between different tissues and organs of the body.",TAS GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA