go_id,ontology,go_term,term_definition,evidence
GO:0000165,BP,"MAPK cascade","An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.",TAS
GO:0002437,BP,"inflammatory response to antigenic stimulus","An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.",IEP
GO:0004713,MF,"protein tyrosine kinase activity","Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.",IEA
GO:0004914,MF,"interleukin-5 receptor activity","Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",TAS
GO:0005088,MF,"Ras guanyl-nucleotide exchange factor activity","Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ras superfamily. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.",TAS
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0005622,CC,intracellular,"The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.",IEA
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0007165,BP,"signal transduction","The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.",IEA
GO:0008283,BP,"cell proliferation","The multiplication or reproduction of cells, resulting in the expansion of a cell population.",IEA
GO:0016021,CC,"integral component of membrane","The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IEA
GO:0018108,BP,"peptidyl-tyrosine phosphorylation","The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.",IEA
GO:0032674,BP,"regulation of interleukin-5 production","Any process that modulates the frequency, rate, or extent of interleukin-5 production.",IEA
GO:0038043,BP,"interleukin-5-mediated signaling pathway","A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.",IEA
GO:0043547,BP,"positive regulation of GTPase activity","Any process that activates or increases the activity of a GTPase.",IEA