go_id,ontology,go_term,term_definition,evidence GO:0004859,MF,"phospholipase inhibitor activity","Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.",IDA GO:0005509,MF,"calcium ion binding","Interacting selectively and non-covalently with calcium ions (Ca2+).",IDA GO:0005543,MF,"phospholipid binding","Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.",IDA GO:0005544,MF,"calcium-dependent phospholipid binding","Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.",IDA GO:0005622,CC,intracellular,"The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.",IEA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005925,CC,"focal adhesion","Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.",IDA GO:0007165,BP,"signal transduction","The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.",IEA GO:0007596,BP,"blood coagulation","The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.",TAS GO:0009897,CC,"external side of plasma membrane","The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.",IBA GO:0010033,BP,"response to organic substance","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.",TAS GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA GO:0043066,BP,"negative regulation of apoptotic process","Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.",IMP GO:0043086,BP,"negative regulation of catalytic activity","Any process that stops or reduces the activity of an enzyme.",IEA GO:0050819,BP,"negative regulation of coagulation","Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.",IEA GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA GO:0072563,CC,"endothelial microparticle","A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell.",IEA