go_id,ontology,go_term,term_definition,evidence
GO:0000166,MF,"nucleotide binding","Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.",IEA
GO:0001837,BP,"epithelial to mesenchymal transition","A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",IMP
GO:0003700,MF,"transcription factor activity, sequence-specific DNA binding","Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.",IMP
GO:0003723,MF,"RNA binding","Interacting selectively and non-covalently with an RNA molecule or a portion thereof.",IEA
GO:0003729,MF,"mRNA binding","Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.",IBA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0030529,CC,"intracellular ribonucleoprotein complex","An intracellular macromolecular complex containing both protein and RNA molecules.",IDA
GO:0043565,MF,"sequence-specific DNA binding","Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.",ISS
GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA
GO:0045893,BP,"positive regulation of transcription, DNA-templated","Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.",IDA
GO:0090575,CC,"RNA polymerase II transcription factor complex","A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase II.",IBA|ISS