go_id,ontology,go_term,term_definition,evidence
GO:0000139,CC,"Golgi membrane","The lipid bilayer surrounding any of the compartments of the Golgi apparatus.",IEA
GO:0002381,BP,"immunoglobulin production involved in immunoglobulin mediated immune response","The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.",IDA
GO:0002455,BP,"humoral immune response mediated by circulating immunoglobulin","An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.",IDA
GO:0005765,CC,"lysosomal membrane","The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.",TAS
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0006955,BP,"immune response","Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.",TAS
GO:0010008,CC,"endosome membrane","The lipid bilayer surrounding an endosome.",TAS
GO:0012507,CC,"ER to Golgi transport vesicle membrane","The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.",IBA|TAS
GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA
GO:0019886,BP,"antigen processing and presentation of exogenous peptide antigen via MHC class II","The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.",TAS
GO:0030658,CC,"transport vesicle membrane","The lipid bilayer surrounding a transport vesicle.",TAS
GO:0030666,CC,"endocytic vesicle membrane","The lipid bilayer surrounding an endocytic vesicle.",TAS
GO:0030669,CC,"clathrin-coated endocytic vesicle membrane","The lipid bilayer surrounding a clathrin-coated endocytic vesicle.",TAS
GO:0031295,BP,"T cell costimulation","The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.",TAS
GO:0032395,MF,"MHC class II receptor activity","Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",NAS
GO:0032588,CC,"trans-Golgi network membrane","The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.",IDA
GO:0042605,MF,"peptide antigen binding","Interacting selectively and non-covalently with an antigen peptide.",ISS
GO:0042613,CC,"MHC class II protein complex","A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.",IDA
GO:0050852,BP,"T cell receptor signaling pathway","A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.",TAS
GO:0060333,BP,"interferon-gamma-mediated signaling pathway","A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.",TAS
GO:0071556,CC,"integral component of lumenal side of endoplasmic reticulum membrane","The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.",TAS