go_id,ontology,go_term,term_definition,evidence GO:0000139,CC,"Golgi membrane","The lipid bilayer surrounding any of the compartments of the Golgi apparatus.",IEA GO:0005765,CC,"lysosomal membrane","The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.",TAS GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA GO:0005887,CC,"integral component of plasma membrane","The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IDA GO:0006955,BP,"immune response","Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.",TAS GO:0010008,CC,"endosome membrane","The lipid bilayer surrounding an endosome.",TAS GO:0012507,CC,"ER to Golgi transport vesicle membrane","The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.",IBA|TAS GO:0019886,BP,"antigen processing and presentation of exogenous peptide antigen via MHC class II","The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.",TAS GO:0030658,CC,"transport vesicle membrane","The lipid bilayer surrounding a transport vesicle.",TAS GO:0030666,CC,"endocytic vesicle membrane","The lipid bilayer surrounding an endocytic vesicle.",TAS GO:0030669,CC,"clathrin-coated endocytic vesicle membrane","The lipid bilayer surrounding a clathrin-coated endocytic vesicle.",TAS GO:0031295,BP,"T cell costimulation","The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.",TAS GO:0032395,MF,"MHC class II receptor activity","Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",NAS GO:0032588,CC,"trans-Golgi network membrane","The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.",IDA GO:0042613,CC,"MHC class II protein complex","A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.",IDA GO:0050852,BP,"T cell receptor signaling pathway","A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.",TAS GO:0060333,BP,"interferon-gamma-mediated signaling pathway","A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.",TAS GO:0071556,CC,"integral component of lumenal side of endoplasmic reticulum membrane","The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.",TAS