go_id,ontology,go_term,term_definition,evidence
GO:0000775,CC,"chromosome, centromeric region","The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.",TAS
GO:0004386,MF,"helicase activity","Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix.",IEA
GO:0005524,MF,"ATP binding","Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",IEA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005721,CC,"pericentric heterochromatin","Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.",IDA
GO:0006346,BP,"methylation-dependent chromatin silencing","Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.",IBA
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0007067,BP,"mitotic nuclear division","A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",IEA
GO:0007275,BP,"multicellular organism development","The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",IEA
GO:0010216,BP,"maintenance of DNA methylation","Any process involved in maintaining the methylation state of a nucleotide sequence.",IDA
GO:0031508,BP,"pericentric heterochromatin assembly","The assembly of chromatin into heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.",IEA
GO:0046651,BP,"lymphocyte proliferation","The expansion of a lymphocyte population by cell division.",ISS
GO:0051301,BP,"cell division","The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.",IEA