go_id,ontology,go_term,term_definition,evidence GO:0000122,BP,"negative regulation of transcription from RNA polymerase II promoter","Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IDA|ISS GO:0000786,CC,nucleosome,"A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.",NAS GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005719,CC,"nuclear euchromatin","The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin.",IEA GO:0006334,BP,"nucleosome assembly","The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.",IDA GO:0016584,BP,"nucleosome positioning","Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.",IDA GO:0031490,MF,"chromatin DNA binding","Interacting selectively and non-covalently with DNA that is assembled into chromatin.",ISS GO:0035327,CC,"transcriptionally active chromatin","The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.",ISS GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA GO:0080182,BP,"histone H3-K4 trimethylation","The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.",IMP GO:0098532,BP,"histone H3-K27 trimethylation","The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone.",IEA