| GO ID | GO:0046627 | 
| Ontology | BP | 
| GO Term | negative regulation of insulin receptor signaling pathway | 
| Definition | Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling. | 
| Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location | 
|---|---|---|---|---|
| 
             SOCS2  | 
          
             suppressor of cytokine signaling 2  | 
          
             8835  | 
          
             O14508  | 
          
             chr12: 93,569,814-93,583,487  | 
        
| 
             SOCS3  | 
          
             suppressor of cytokine signaling 3  | 
          
             9021  | 
          
             O14543  | 
          
             chr17: 78,356,778-78,360,077  | 
        
| 
             MSTN  | 
          
             myostatin  | 
          
             2660  | 
          
             O14793  | 
          
             chr2: 190,055,697-190,062,729  | 
        
| 
             SOCS1  | 
          
             suppressor of cytokine signaling 1  | 
          
             8651  | 
          
             O15524  | 
          
             chr16: 11,254,405-11,256,179  | 
        
| 
             IL1B  | 
          
             interleukin 1 beta  | 
          
             3553  | 
          
             P01584  | 
          
             chr2: 112,829,751-112,836,903  | 
        
| 
             AHSG  | 
          
             alpha-2-HS-glycoprotein  | 
          
             197  | 
          
             P02765  | 
          
             chr3: 186,612,923-186,621,318  | 
        
| 
             PRKCB  | 
          
             protein kinase C, beta  | 
          
             5579  | 
          
             P05771  | 
          
             chr16: 23,836,001-24,220,611  | 
        
| 
             PTPN2  | 
          
             protein tyrosine phosphatase, non-receptor type 2  | 
          
             5771  | 
          
             P17706  | 
          
             chr18: 12,785,478-12,929,643  | 
        
| 
             ENPP1  | 
          
             ectonucleotide pyrophosphatase/phosphodiesterase 1  | 
          
             5167  | 
          
             P22413  | 
          
             chr6: 131,808,016-131,895,155  | 
        
| 
             IRS1  | 
          
             insulin receptor substrate 1  | 
          
             3667  | 
          
             P35568  | 
          
             chr2: 226,731,317-226,799,759  | 
        
| 
             TSC2  | 
          
             tuberous sclerosis 2  | 
          
             7249  | 
          
             P49815  | 
          
             chr16: 2,047,465-2,088,720  | 
        
| 
             RELA  | 
          
             v-rel avian reticuloendotheliosis viral oncogene homolog A  | 
          
             5970  | 
          
             Q04206  | 
          
             chr11: 65,653,596-65,663,094  | 
        
| 
             PRKCQ  | 
          
             protein kinase C, theta  | 
          
             5588  | 
          
             Q04759  | 
          
             chr10: 6,427,143-6,580,301  | 
        
| 
             PRKCD  | 
          
             protein kinase C, delta  | 
          
             5580  | 
          
             Q05655  | 
          
             chr3: 53,156,009-53,192,717  | 
        
| 
             GRB10  | 
          
             growth factor receptor bound protein 10  | 
          
             2887  | 
          
             Q13322  | 
          
             chr7: 50,590,063-50,793,462  | 
        
| 
             KANK1  | 
          
             KN motif and ankyrin repeat domains 1  | 
          
             23189  | 
          
             Q14678  | 
          
             chr9: 470,291-746,106  | 
        
| 
             PID1  | 
          
             phosphotyrosine interaction domain containing 1  | 
          
             55022  | 
          
             Q7Z2X4  | 
          
             chr2: 228,850,526-229,271,285  | 
        
| 
             INPP5K  | 
          
             inositol polyphosphate-5-phosphatase K  | 
          
             51763  | 
          
             Q9BT40  | 
          
             chr17: 1,494,571-1,516,888  | 
        
| 
             LMBRD1  | 
          
             LMBR1 domain containing 1  | 
          
             55788  | 
          
             Q9NUN5  | 
          
             chr6: 69,675,802-69,797,111  |