GO ID | GO:0046627 |
Ontology | BP |
GO Term | negative regulation of insulin receptor signaling pathway |
Definition | Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling. |
Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
---|---|---|---|---|
SOCS2 |
suppressor of cytokine signaling 2 |
8835 |
O14508 |
chr12: 93,569,814-93,583,487 |
SOCS3 |
suppressor of cytokine signaling 3 |
9021 |
O14543 |
chr17: 78,356,778-78,360,077 |
MSTN |
myostatin |
2660 |
O14793 |
chr2: 190,055,697-190,062,729 |
SOCS1 |
suppressor of cytokine signaling 1 |
8651 |
O15524 |
chr16: 11,254,405-11,256,179 |
IL1B |
interleukin 1 beta |
3553 |
P01584 |
chr2: 112,829,751-112,836,903 |
AHSG |
alpha-2-HS-glycoprotein |
197 |
P02765 |
chr3: 186,612,923-186,621,318 |
PRKCB |
protein kinase C, beta |
5579 |
P05771 |
chr16: 23,836,001-24,220,611 |
PTPN2 |
protein tyrosine phosphatase, non-receptor type 2 |
5771 |
P17706 |
chr18: 12,785,478-12,929,643 |
ENPP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
5167 |
P22413 |
chr6: 131,808,016-131,895,155 |
IRS1 |
insulin receptor substrate 1 |
3667 |
P35568 |
chr2: 226,731,317-226,799,759 |
TSC2 |
tuberous sclerosis 2 |
7249 |
P49815 |
chr16: 2,047,465-2,088,720 |
RELA |
v-rel avian reticuloendotheliosis viral oncogene homolog A |
5970 |
Q04206 |
chr11: 65,653,596-65,663,094 |
PRKCQ |
protein kinase C, theta |
5588 |
Q04759 |
chr10: 6,427,143-6,580,301 |
PRKCD |
protein kinase C, delta |
5580 |
Q05655 |
chr3: 53,156,009-53,192,717 |
GRB10 |
growth factor receptor bound protein 10 |
2887 |
Q13322 |
chr7: 50,590,063-50,793,462 |
KANK1 |
KN motif and ankyrin repeat domains 1 |
23189 |
Q14678 |
chr9: 470,291-746,106 |
PID1 |
phosphotyrosine interaction domain containing 1 |
55022 |
Q7Z2X4 |
chr2: 228,850,526-229,271,285 |
INPP5K |
inositol polyphosphate-5-phosphatase K |
51763 |
Q9BT40 |
chr17: 1,494,571-1,516,888 |
LMBRD1 |
LMBR1 domain containing 1 |
55788 |
Q9NUN5 |
chr6: 69,675,802-69,797,111 |