Gene Ontology Description

GO ID GO:0042059
Ontology BP
GO Term negative regulation of epidermal growth factor receptor signaling pathway
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

SPRY2

sprouty RTK signaling antagonist 2

10253

O43597

chr13: 80,335,976-80,340,951

SPRY1

sprouty RTK signaling antagonist 1

10252

O43609

chr4: 123,396,795-123,403,760

STAM2

signal transducing adaptor molecule 2

10254

O75886

chr2: 152,116,801-152,175,992

AP2A2

adaptor related protein complex 2, alpha 2 subunit

161

O94973

chr11: 924,894-1,012,245

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

CLTA

clathrin, light chain A

1211

P09496

chr9: 36,190,856-36,304,781

UBC

ubiquitin C

7316

P0CG48

chr12: 124,911,604-124,917,368

PTPN2

protein tyrosine phosphatase, non-receptor type 2

5771

P17706

chr18: 12,785,478-12,929,643

NUP62

nucleoporin 62kDa

23636

P37198

chr19: 49,906,825-49,929,763

EPS15

epidermal growth factor receptor pathway substrate 15

2060

P42566

chr1: 51,354,263-51,519,328

AP2S1

adaptor related protein complex 2 sigma 1 subunit

1175

P53680

chr19: 46,838,136-46,850,992

CDC42

cell division cycle 42

998

P60953

chr1: 22,052,627-22,092,946

RPS27A

ribosomal protein S27a

6233

P62979

chr2: 55,231,903-55,235,853

UBA52

ubiquitin A-52 residue ribosomal protein fusion product 1

7311

P62987

chr19: 18,571,730-18,577,550

GRB2

growth factor receptor bound protein 2

2885

P62993

chr17: 75,318,076-75,405,709

AP2B1

adaptor related protein complex 2, beta 1 subunit

163

P63010

chr17: 35,578,046-35,726,409

PTPRJ

protein tyrosine phosphatase, receptor type, J

5795

Q12913

chr11: 47,980,558-48,170,841

ARHGEF7

Rho guanine nucleotide exchange factor 7

8874

Q14155

chr13: 111,114,559-111,305,737

STAM

signal transducing adaptor molecule

8027

Q92783

chr10: 17,644,125-17,715,914

AP2M1

adaptor related protein complex 2, mu 1 subunit

1173

Q96CW1

chr3: 184,174,689-184,184,091

SH3GL2

SH3-domain GRB2-like 2

6456

Q99962

chr9: 17,579,082-17,797,129

RNF126

ring finger protein 126

55658

Q9BV68

chr19: 647,526-663,277