| GO ID | GO:0036297 |
| Ontology | BP |
| GO Term | interstrand cross-link repair |
| Definition | Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. |
| Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
|---|---|---|---|---|
|
STRA13 |
stimulated by retinoic acid 13 |
201254 |
A8MT69 |
chr17: 82,018,702-82,024,107 |
|
FANCG |
Fanconi anemia complementation group G |
2189 |
O15287 |
chr9: 35,073,835-35,080,016 |
|
RAD51D |
RAD51 paralog D |
5892 |
O75771 |
chr17: 35,092,208-35,121,522 |
|
RNF8 |
ring finger protein 8, E3 ubiquitin protein ligase |
9025 |
O76064 |
chr6: 37,353,972-37,394,738 |
|
USP1 |
ubiquitin specific peptidase 1 |
7398 |
O94782 |
chr1: 62,436,297-62,451,804 |
|
ERCC1 |
excision repair cross-complementation group 1 |
2067 |
P07992 |
chr19: 45,407,333-45,478,828 |
|
UBC |
ubiquitin C |
7316 |
P0CG48 |
chr12: 124,911,604-124,917,368 |
|
RPA3 |
replication protein A3 |
6119 |
P35244 |
chr7: 7,636,518-7,718,607 |
|
RPS27A |
ribosomal protein S27a |
6233 |
P62979 |
chr2: 55,231,903-55,235,853 |
|
UBA52 |
ubiquitin A-52 residue ribosomal protein fusion product 1 |
7311 |
P62987 |
chr19: 18,571,730-18,577,550 |
|
FAAP100 |
Fanconi anemia core complex associated protein 100 |
80233 |
Q0VG06 |
chr17: 81,539,885-81,553,961 |
|
FAAP20 |
Fanconi anemia core complex associated protein 20 |
199990 |
Q6NZ36 |
chr1: 2,184,461-2,212,720 |
|
FANCM |
Fanconi anemia complementation group M |
57697 |
Q8IYD8 |
chr14: 45,135,940-45,200,890 |
|
APITD1 |
apoptosis-inducing, TAF9-like domain 1 |
378708 |
Q8N2Z9 |
chr1: 10,430,443-10,442,809 |
|
FANCB |
Fanconi anemia complementation group B |
2187 |
Q8NB91 |
chrX: 14,843,407-14,873,069 |
|
ATRIP |
ATR interacting protein |
84126 |
Q8WXE1 |
chr3: 48,446,710-48,465,716 |
|
ERCC4 |
excision repair cross-complementation group 4 |
2072 |
Q92889 |
chr16: 13,920,157-13,952,345 |
|
EME1 |
essential meiotic structure-specific endonuclease 1 |
146956 |
Q96AY2 |
chr17: 50,373,220-50,381,483 |
|
RAD51AP1 |
RAD51 associated protein 1 |
10635 |
Q96B01 |
chr12: 4,538,798-4,560,048 |
|
DCLRE1C |
DNA cross-link repair 1C |
64421 |
Q96SD1 |
chr10: 14,897,359-14,954,432 |
|
FANCD2 |
Fanconi anemia complementation group D2 |
2177 |
Q9BXW9 |
chr3: 10,026,414-10,101,930 |
|
NUCKS1 |
nuclear casein kinase and cyclin-dependent kinase substrate 1 |
64710 |
Q9H1E3 |
chr1: 205,712,819-205,750,276 |
|
FANCE |
Fanconi anemia complementation group E |
2178 |
Q9HB96 |
chr6: 35,452,361-35,467,103 |
|
UBE2T |
ubiquitin conjugating enzyme E2T |
29089 |
Q9NPD8 |
chr1: 202,331,657-202,341,980 |
|
FANCI |
Fanconi anemia complementation group I |
55215 |
Q9NVI1 |
chr15: 89,243,949-89,317,261 |
|
FAN1 |
FANCD2/FANCI-associated nuclease 1 |
22909 |
Q9Y2M0 |
chr15: 30,903,852-30,943,108 |