Gene Ontology Description

GO ID GO:0036297
Ontology BP
GO Term interstrand cross-link repair
Definition Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

STRA13

stimulated by retinoic acid 13

201254

A8MT69

chr17: 82,018,702-82,024,107

FANCG

Fanconi anemia complementation group G

2189

O15287

chr9: 35,073,835-35,080,016

RAD51D

RAD51 paralog D

5892

O75771

chr17: 35,092,208-35,121,522

RNF8

ring finger protein 8, E3 ubiquitin protein ligase

9025

O76064

chr6: 37,353,972-37,394,738

USP1

ubiquitin specific peptidase 1

7398

O94782

chr1: 62,436,297-62,451,804

ERCC1

excision repair cross-complementation group 1

2067

P07992

chr19: 45,407,333-45,478,828

UBC

ubiquitin C

7316

P0CG48

chr12: 124,911,604-124,917,368

RPA3

replication protein A3

6119

P35244

chr7: 7,636,518-7,718,607

RPS27A

ribosomal protein S27a

6233

P62979

chr2: 55,231,903-55,235,853

UBA52

ubiquitin A-52 residue ribosomal protein fusion product 1

7311

P62987

chr19: 18,571,730-18,577,550

FAAP100

Fanconi anemia core complex associated protein 100

80233

Q0VG06

chr17: 81,539,885-81,553,961

FAAP20

Fanconi anemia core complex associated protein 20

199990

Q6NZ36

chr1: 2,184,461-2,212,720

FANCM

Fanconi anemia complementation group M

57697

Q8IYD8

chr14: 45,135,940-45,200,890

APITD1

apoptosis-inducing, TAF9-like domain 1

378708

Q8N2Z9

chr1: 10,430,443-10,442,809

FANCB

Fanconi anemia complementation group B

2187

Q8NB91

chrX: 14,843,407-14,873,069

ATRIP

ATR interacting protein

84126

Q8WXE1

chr3: 48,446,710-48,465,716

ERCC4

excision repair cross-complementation group 4

2072

Q92889

chr16: 13,920,157-13,952,345

EME1

essential meiotic structure-specific endonuclease 1

146956

Q96AY2

chr17: 50,373,220-50,381,483

RAD51AP1

RAD51 associated protein 1

10635

Q96B01

chr12: 4,538,798-4,560,048

DCLRE1C

DNA cross-link repair 1C

64421

Q96SD1

chr10: 14,897,359-14,954,432

FANCD2

Fanconi anemia complementation group D2

2177

Q9BXW9

chr3: 10,026,414-10,101,930

NUCKS1

nuclear casein kinase and cyclin-dependent kinase substrate 1

64710

Q9H1E3

chr1: 205,712,819-205,750,276

FANCE

Fanconi anemia complementation group E

2178

Q9HB96

chr6: 35,452,361-35,467,103

UBE2T

ubiquitin conjugating enzyme E2T

29089

Q9NPD8

chr1: 202,331,657-202,341,980

FANCI

Fanconi anemia complementation group I

55215

Q9NVI1

chr15: 89,243,949-89,317,261

FAN1

FANCD2/FANCI-associated nuclease 1

22909

Q9Y2M0

chr15: 30,903,852-30,943,108