| GO ID | GO:0014704 |
| Ontology | CC |
| GO Term | intercalated disc |
| Definition | A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells. |
| Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
|---|---|---|---|---|
|
OBSL1 |
obscurin-like 1 |
23363 |
O75147 |
chr2: 219,550,729-219,571,859 |
|
ATP1B1 |
ATPase, Na+/K+ transporting, beta 1 polypeptide |
481 |
P05026 |
chr1: 169,105,697-169,132,722 |
|
ITGB1 |
integrin subunit beta 1 |
3688 |
P05556 |
chr10: 32,900,319-33,005,792 |
|
JUP |
junction plakoglobin |
3728 |
P14923 |
chr17: 41,754,604-41,786,931 |
|
DSP |
desmoplakin |
1832 |
P15924 |
chr6: 7,541,575-7,586,717 |
|
GJA1 |
gap junction protein alpha 1 |
2697 |
P17302 |
chr6: 121,435,692-121,449,727 |
|
DES |
desmin |
1674 |
P17661 |
chr2: 219,418,377-219,426,739 |
|
CDH2 |
cadherin 2, type 1, N-cadherin (neuronal) |
1000 |
P19022 |
chr18: 27,950,966-28,177,446 |
|
CTNNA1 |
catenin alpha 1 |
1495 |
P35221 |
chr5: 138,610,967-138,935,034 |
|
GJA5 |
gap junction protein alpha 5 |
2702 |
P36382 |
chr1: 147,756,199-147,773,362 |
|
GJC1 |
gap junction protein gamma 1 |
10052 |
P36383 |
chr17: 44,798,448-44,830,816 |
|
ATP1A2 |
ATPase, Na+/K+ transporting, alpha 2 polypeptide |
477 |
P50993 |
chr1: 160,115,759-160,143,591 |
|
HAMP |
hepcidin antimicrobial peptide |
57817 |
P81172 |
chr19: 35,280,716-35,285,143 |
|
ANK2 |
ankyrin 2, neuronal |
287 |
Q01484 |
chr4: 112,818,109-113,383,740 |
|
DSC2 |
desmocollin 2 |
1824 |
Q02487 |
chr18: 31,058,840-31,102,415 |
|
YWHAH |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
7533 |
Q04917 |
chr22: 31,944,461-31,957,603 |
|
TJP1 |
tight junction protein 1 |
7082 |
Q07157 |
chr15: 29,699,367-29,968,865 |
|
ANK3 |
ankyrin 3, node of Ranvier (ankyrin G) |
288 |
Q12955 |
chr10: 60,026,298-60,733,490 |
|
DLG1 |
discs, large homolog 1 (Drosophila) |
1739 |
Q12959 |
chr3: 197,042,560-197,299,300 |
|
AKAP6 |
A-kinase anchoring protein 6 |
9472 |
Q13023 |
chr14: 32,329,273-32,837,681 |
|
CAMK2D |
calcium/calmodulin-dependent protein kinase II delta |
817 |
Q13557 |
chr4: 113,451,032-113,761,927 |
|
DSG2 |
desmoglein 2 |
1829 |
Q14126 |
chr18: 31,498,043-31,549,008 |
|
KCNJ11 |
potassium channel, inwardly rectifying subfamily J, member 11 |
3767 |
Q14654 |
chr11: 17,385,859-17,389,331 |
|
TMEM65 |
transmembrane protein 65 |
157378 |
Q6PI78 |
chr8: 124,306,189-124,372,692 |
|
FGF13 |
fibroblast growth factor 13 |
2258 |
Q92913 |
chrX: 138,614,731-139,222,777 |
|
PKP2 |
plakophilin 2 |
5318 |
Q99959 |
chr12: 32,790,745-32,896,840 |
|
RANGRF |
RAN guanine nucleotide release factor |
29098 |
Q9HD47 |
chr17: 8,288,497-8,290,092 |