Gene Ontology Description

GO ID GO:0014066
Ontology BP
GO Term regulation of phosphatidylinositol 3-kinase signaling
Definition Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

5293

O00329

chr1: 9,651,732-9,729,114

EREG

epiregulin

2069

O14944

chr4: 74,365,143-74,388,751

PIP5K1B

phosphatidylinositol-4-phosphate 5-kinase, type I, beta

8395

O14986

chr9: 68,705,414-69,009,176

PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

23396

O60331

chr19: 3,630,183-3,700,479

FGF18

fibroblast growth factor 18

8817

O76093

chr5: 171,419,656-171,457,623

FGF19

fibroblast growth factor 19

9965

O95750

chr11: 69,698,232-69,704,642

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

PDGFB

platelet-derived growth factor beta polypeptide

5155

P01127

chr22: 39,223,359-39,244,751

PDGFA

platelet-derived growth factor alpha polypeptide

5154

P04085

chr7: 497,258-520,296

ERBB2

erb-b2 receptor tyrosine kinase 2

2064

P04626

chr17: 39,687,914-39,730,426

FYN

FYN proto-oncogene, Src family tyrosine kinase

2534

P06241

chr6: 111,660,332-111,873,452

FGF2

fibroblast growth factor 2 (basic)

2247

P09038

chr4: 122,826,708-122,898,236

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

5159

P09619

chr5: 150,113,837-150,155,872

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

3815

P10721

chr4: 54,657,918-54,740,715

CD28

CD28 molecule

940

P10747

chr2: 203,706,475-203,738,912

FGFR1

fibroblast growth factor receptor 1

2260

P11362

chr8: 38,411,138-38,468,834

VAV1

vav guanine nucleotide exchange factor 1

7409

P15498

chr19: 6,772,714-6,857,366

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

5156

P16234

chr4: 54,229,097-54,298,247

KITLG

KIT ligand

4254

P21583

chr12: 88,492,793-88,580,851

FGF7

fibroblast growth factor 7

2252

P21781

chr15: 49,423,096-49,488,775

FGFR2

fibroblast growth factor receptor 2

2263

P21802

chr10: 121,478,334-121,598,458

ERBB3

erb-b2 receptor tyrosine kinase 3

2065

P21860

chr12: 56,079,857-56,103,505

MAPK3

mitogen-activated protein kinase 3

5595

P27361

chr16: 30,114,105-30,123,506

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

5295

P27986

chr5: 68,215,720-68,301,821

MAPK1

mitogen-activated protein kinase 1

5594

P28482

chr22: 21,754,500-21,867,680

FGF9

fibroblast growth factor 9

2254

P31371

chr13: 21,671,383-21,704,498

AKT1

v-akt murine thymoma viral oncogene homolog 1

207

P31749

chr14: 104,769,349-104,795,751

BTC

betacellulin

685

P35070

chr4: 74,744,759-74,794,686

IRS1

insulin receptor substrate 1

3667

P35568

chr2: 226,731,317-226,799,759

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

5290

P42336

chr3: 179,148,114-179,240,093

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

5291

P42338

chr3: 138,652,699-138,834,938

IER3

immediate early response 3

8870

P46695

chr6: 30,743,199-30,744,554

GRB2

growth factor receptor bound protein 2

2885

P62993

chr17: 75,318,076-75,405,709

PIP4K2B

phosphatidylinositol-5-phosphate 4-kinase, type II, beta

8396

P78356

chr17: 38,765,689-38,800,126

NRG1

neuregulin 1

3084

Q02297

chr8: 31,639,386-32,767,959

PTPN11

protein tyrosine phosphatase, non-receptor type 11

5781

Q06124

chr12: 112,418,351-112,509,913

PPP2R5C

protein phosphatase 2 regulatory subunit B', gamma

5527

Q13362

chr14: 101,761,798-101,927,989

GAB1

GRB2 associated binding protein 1

2549

Q13480

chr4: 143,336,762-143,474,568

PPP2R5B

protein phosphatase 2 regulatory subunit B', beta

5526

Q15173

chr11: 64,917,553-64,934,473

ERBB4

erb-b2 receptor tyrosine kinase 4

2066

Q15303

chr2: 211,375,717-212,538,841

FRS2

fibroblast growth factor receptor substrate 2

10818

Q8WU20

chr12: 69,470,349-69,579,789

HBEGF

heparin-binding EGF-like growth factor

1839

Q99075

chr5: 140,332,843-140,346,631

KL

klotho

9365

Q9UEF7

chr13: 33,016,433-33,066,145

FBXL2

F-box and leucine-rich repeat protein 2

25827

Q9UKC9

chr3: 33,277,025-33,403,662

IRS2

insulin receptor substrate 2

8660

Q9Y4H2

chr13: 109,752,698-109,786,568