GO ID | GO:0010951 |
Ontology | BP |
GO Term | negative regulation of endopeptidase activity |
Definition | Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. |
Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
---|---|---|---|---|
SPINT2 |
serine peptidase inhibitor, Kunitz type, 2 |
10653 |
O43291 |
chr19: 38,244,035-38,292,614 |
PAPLN |
papilin, proteoglycan-like sulfated glycoprotein |
89932 |
O95428 |
chr14: 73,237,497-73,274,640 |
PTTG1 |
pituitary tumor-transforming 1 |
9232 |
O95997 |
chr5: 160,421,822-160,428,744 |
SERPINC1 |
serpin peptidase inhibitor, clade C (antithrombin), member 1 |
462 |
P01008 |
chr1: 173,903,804-173,917,378 |
SERPINA1 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
5265 |
P01009 |
chr14: 94,376,747-94,390,693 |
SERPINA3 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
12 |
P01011 |
chr14: 94,612,377-94,624,055 |
AGT |
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
183 |
P01019 |
chr1: 230,702,523-230,714,297 |
A2M |
alpha-2-macroglobulin |
2 |
P01023 |
chr12: 9,067,664-9,116,229 |
C3 |
complement component 3 |
718 |
P01024 |
chr19: 6,677,704-6,730,562 |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
7076 |
P01033 |
chrX: 47,582,313-47,586,789 |
CSTA |
cystatin A |
1475 |
P01040 |
chr3: 122,325,244-122,341,972 |
KNG1 |
kininogen 1 |
3827 |
P01042 |
chr3: 186,717,276-186,743,954 |
AMBP |
alpha-1-microglobulin/bikunin precursor |
259 |
P02760 |
chr9: 114,060,127-114,078,472 |
AHSG |
alpha-2-HS-glycoprotein |
197 |
P02765 |
chr3: 186,612,923-186,621,318 |
SLPI |
secretory leukocyte peptidase inhibitor |
6590 |
P03973 |
chr20: 45,252,239-45,254,564 |
VTN |
vitronectin |
7448 |
P04004 |
chr17: 28,367,276-28,373,091 |
CSTB |
cystatin B |
1476 |
P04080 |
chr21: 43,772,511-43,776,445 |
APP |
amyloid beta (A4) precursor protein |
351 |
P05067 |
chr21: 25,880,550-26,171,128 |
SERPINE1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
5054 |
P05121 |
chr7: 101,127,089-101,139,266 |
SERPINA5 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
5104 |
P05154 |
chr14: 94,561,442-94,593,120 |
SERPING1 |
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
710 |
P05155 |
chr11: 57,597,387-57,614,853 |
SERPINE2 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
5270 |
P07093 |
chr2: 223,975,112-224,039,319 |
FURIN |
furin (paired basic amino acid cleaving enzyme) |
5045 |
P09958 |
chr15: 90,868,592-90,883,458 |
C4A |
complement component 4A (Rodgers blood group) |
720 |
P0C0L4 |
chr6: 31,982,024-32,002,681 |
C4B |
complement component 4B (Chido blood group) |
721 |
P0C0L5 |
chr6: 32,014,762-32,035,418 |
TFPI |
tissue factor pathway inhibitor |
7035 |
P10646 |
chr2: 187,464,230-187,565,760 |
COL6A3 |
collagen, type VI, alpha 3 |
1293 |
P12111 |
chr2: 237,324,003-237,414,375 |
TIMP2 |
TIMP metallopeptidase inhibitor 2 |
7077 |
P16035 |
chr17: 78,852,977-78,925,387 |
CAST |
calpastatin |
831 |
P20810 |
chr5: 96,525,267-96,779,595 |
ANOS1 |
anosmin 1 |
3730 |
P23352 |
chrX: 8,528,874-8,732,186 |
SERPINB3 |
serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
6317 |
P29508 |
chr18: 63,655,197-63,661,963 |
PEBP1 |
phosphatidylethanolamine binding protein 1 |
5037 |
P30086 |
chr12: 118,135,858-118,145,584 |
SERPINB1 |
serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
1992 |
P30740 |
chr6: 2,832,332-2,842,006 |
AKT1 |
v-akt murine thymoma viral oncogene homolog 1 |
207 |
P31749 |
chr14: 104,769,349-104,795,751 |
SERPINB5 |
serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
5268 |
P36952 |
chr18: 63,476,761-63,505,085 |
SERPINF1 |
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
5176 |
P36955 |
chr17: 1,761,959-1,777,574 |
TFPI2 |
tissue factor pathway inhibitor 2 |
7980 |
P48307 |
chr7: 93,885,397-93,890,991 |
SERPINB4 |
serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
6318 |
P48594 |
chr18: 63,637,259-63,644,298 |
SERPINB9 |
serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
5272 |
P50453 |
chr6: 2,887,266-2,903,280 |
SERPINH1 |
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
871 |
P50454 |
chr11: 75,562,056-75,572,783 |
COL4A3 |
collagen, type IV, alpha 3 (Goodpasture antigen) |
1285 |
Q01955 |
chr2: 227,164,565-227,314,792 |
APLP2 |
amyloid beta (A4) precursor-like protein 2 |
334 |
Q06481 |
chr11: 130,069,837-130,144,811 |
BST2 |
bone marrow stromal cell antigen 2 |
684 |
Q10589 |
chr19: 17,402,939-17,405,648 |
SPP2 |
secreted phosphoprotein 2 |
6694 |
Q13103 |
chr2: 234,050,679-234,077,134 |
WFDC2 |
WAP four-disulfide core domain 2 |
10406 |
Q14508 |
chr20: 45,469,706-45,481,532 |
CARD16 |
caspase recruitment domain family member 16 |
114769 |
Q5EG05 |
chr11: 105,041,326-105,101,431 |
ITIH5 |
inter-alpha-trypsin inhibitor heavy chain family member 5 |
80760 |
Q86UX2 |
chr10: 7,559,270-7,666,998 |
WFDC3 |
WAP four-disulfide core domain 3 |
140686 |
Q8IUB2 |
chr20: 45,747,944-45,791,932 |
SERPINA12 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 |
145264 |
Q8IW75 |
chr14: 94,487,274-94,517,844 |
CPAMD8 |
C3 and PZP-like, alpha-2-macroglobulin domain containing 8 |
27151 |
Q8IZJ3 |
chr19: 16,892,947-17,026,815 |
SPOCK2 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
9806 |
Q92563 |
chr10: 72,059,035-72,089,032 |
SERPINI1 |
serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
5274 |
Q99574 |
chr3: 167,735,243-167,825,568 |
PROL1 |
proline rich, lacrimal 1 |
58503 |
Q99935 |
chr4: 70,397,882-70,410,194 |
SPOCK3 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
50859 |
Q9BQ16 |
chr4: 166,733,384-167,234,796 |
LXN |
latexin |
56925 |
Q9BS40 |
chr3: 158,645,822-158,672,693 |
WFDC1 |
WAP four-disulfide core domain 1 |
58189 |
Q9HC57 |
chr16: 84,294,646-84,329,851 |
CRIM1 |
cysteine rich transmembrane BMP regulator 1 (chordin-like) |
51232 |
Q9NZV1 |
chr2: 36,355,926-36,551,135 |
FETUB |
fetuin B |
26998 |
Q9UGM5 |
chr3: 186,635,969-186,653,141 |
SERPINB13 |
serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
5275 |
Q9UIV8 |
chr18: 63,586,989-63,604,639 |
UCHL5 |
ubiquitin C-terminal hydrolase L5 |
51377 |
Q9Y5K5 |
chr1: 193,012,250-193,060,080 |