Gene Ontology Description

GO ID GO:0006954
Ontology BP
GO Term inflammatory response
Definition The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

TLR4

toll-like receptor 4

7099

O00206

chr9: 117,704,332-117,716,871

TNFRSF11B

tumor necrosis factor receptor superfamily member 11b

4982

O00300

chr8: 118,923,557-118,952,200

PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

5293

O00329

chr1: 9,651,732-9,729,114

TNFRSF10C

tumor necrosis factor receptor superfamily member 10c

8794

O14798

chr8: 23,084,355-23,117,437

TLR3

toll-like receptor 3

7098

O15455

chr4: 186,069,152-186,088,069

IRAK2

interleukin 1 receptor associated kinase 2

3656

O43187

chr3: 10,164,865-10,243,743

RIPK2

receptor interacting serine/threonine kinase 2

8767

O43353

chr8: 89,757,747-89,791,063

CD5L

CD5 molecule like

922

O43866

chr1: 157,830,914-157,898,256

LY75

lymphocyte antigen 75

4065

O60449

chr2: 159,803,355-159,904,749

TPST1

tyrosylprotein sulfotransferase 1

8460

O60507

chr7: 66,205,199-66,420,543

TLR5

toll-like receptor 5

7100

O60602

chr1: 223,109,406-223,143,282

TLR2

toll-like receptor 2

7097

O60603

chr4: 153,701,500-153,705,699

TSPAN2

tetraspanin 2

10100

O60636

chr1: 115,048,011-115,089,500

SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

8482

O75326

chr15: 74,409,289-74,434,467

GPR32

G protein-coupled receptor 32

2854

O75388

chr19: 50,770,464-50,771,732

TNFRSF21

tumor necrosis factor receptor superfamily member 21

27242

O75509

chr6: 47,231,532-47,309,905

RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

9252

O75582

chr14: 90,847,862-91,060,636

TUSC2

tumor suppressor candidate 2

11334

O75896

chr3: 50,320,027-50,328,251

VNN1

vanin 1

8876

O95497

chr6: 132,681,590-132,714,049

SERPINA3

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

12

P01011

chr14: 94,612,377-94,624,055

C3

complement component 3

718

P01024

chr19: 6,677,704-6,730,562

KNG1

kininogen 1

3827

P01042

chr3: 186,717,276-186,743,954

FOS

FBJ murine osteosarcoma viral oncogene homolog

2353

P01100

chr14: 75,278,774-75,282,230

TGFB1

transforming growth factor beta 1

7040

P01137

chr19: 41,301,587-41,353,911

TNF

tumor necrosis factor

7124

P01375

chr6: 31,575,567-31,578,336

IL1A

interleukin 1 alpha

3552

P01583

chr2: 112,773,915-112,784,590

IL1B

interleukin 1 beta

3553

P01584

chr2: 112,829,751-112,836,903

CRP

C-reactive protein, pentraxin-related

1401

P02741

chr1: 159,712,289-159,714,589

ORM1

orosomucoid 1

5004

P02763

chr9: 114,323,056-114,326,475

PPBP

pro-platelet basic protein

5473

P02775

chr4: 73,987,038-73,988,197

PF4

platelet factor 4

5196

P02776

chr4: 73,981,077-73,982,124

ANXA1

annexin A1

301

P04083

chr9: 73,151,757-73,170,393

CYBB

cytochrome b-245, beta polypeptide

1536

P04839

chrX: 37,780,011-37,813,461

ITGB2

integrin subunit beta 2

3689

P05107

chr21: 44,885,953-44,931,989

S100A8

S100 calcium binding protein A8

6279

P05109

chr1: 153,390,032-153,391,188

IL6

interleukin 6

3569

P05231

chr7: 22,725,884-22,732,002

S100A9

S100 calcium binding protein A9

6280

P06702

chr1: 153,357,854-153,361,027

CSF1R

colony stimulating factor 1 receptor

1436

P07333

chr5: 150,053,291-150,113,372

LYN

LYN proto-oncogene, Src family tyrosine kinase

4067

P07948

chr8: 55,879,813-56,014,168

THBS1

thrombospondin 1

7057

P07996

chr15: 39,581,079-39,599,466

NGFR

nerve growth factor receptor

4804

P08138

chr17: 49,495,293-49,515,017

CD14

CD14 molecule

929

P08571

chr5: 140,631,728-140,633,701

KRT16

keratin 16, type I

3868

P08779

chr17: 41,609,778-41,615,899

CXCL1

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

2919

P09341

chr4: 73,869,393-73,871,242

HMGB1

high mobility group box 1

3146

P09429

chr13: 30,456,704-30,617,597

C4A

complement component 4A (Rodgers blood group)

720

P0C0L4

chr6: 31,982,024-32,002,681

C4B

complement component 4B (Chido blood group)

721

P0C0L5

chr6: 32,014,762-32,035,418

CXCL8

chemokine (C-X-C motif) ligand 8

3576

P10145

chr4: 73,740,506-73,743,716

CCL3

chemokine (C-C motif) ligand 3

6348

P10147

chr17: 36,088,256-36,090,169

SPP1

secreted phosphoprotein 1

6696

P10451

chr4: 87,975,650-87,983,426

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

3815

P10721

chr4: 54,657,918-54,740,715

BMP2

bone morphogenetic protein 2

650

P12643

chr20: 6,767,664-6,780,280

CCL4

chemokine (C-C motif) ligand 4

6351

P13236

chr17: 36,103,590-36,105,621

CCL2

chemokine (C-C motif) ligand 2

6347

P13500

chr17: 34,255,218-34,257,203

CCL5

chemokine (C-C motif) ligand 5

6352

P13501

chr17: 35,871,491-35,880,793

SCG2

secretogranin II

7857

P13521

chr2: 223,596,940-223,602,503

MIF

macrophage migration inhibitory factor (glycosylation-inhibiting factor)

4282

P14174

chr22: 23,894,004-23,895,227

ALOX15

arachidonate 15-lipoxygenase

246

P16050

chr17: 4,630,902-4,642,294

SELE

selectin E

6401

P16581

chr1: 169,722,641-169,764,705

CEBPB

CCAAT/enhancer binding protein (C/EBP), beta

1051

P17676

chr20: 50,190,734-50,192,689

SDC1

syndecan 1

6382

P18827

chr2: 20,200,797-20,225,433

NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

4790

P19838

chr4: 102,501,329-102,617,302

CXCL2

chemokine (C-X-C motif) ligand 2

2920

P19875

chr4: 74,097,035-74,099,293

TNFRSF1B

tumor necrosis factor receptor superfamily member 1B

7133

P20333

chr1: 12,167,003-12,209,228

FPR1

formyl peptide receptor 1

2357

P21462

chr19: 51,745,172-51,804,110

TNFAIP3

TNF alpha induced protein 3

7128

P21580

chr6: 137,867,188-137,883,312

C5AR1

complement component 5a receptor 1

728

P21730

chr19: 47,290,023-47,322,066

BMP6

bone morphogenetic protein 6

654

P22004

chr6: 7,726,797-7,881,422

IL10

interleukin 10

3586

P22301

chr1: 206,767,602-206,772,494

GAL

galanin/GMAP prepropeptide

51083

P22466

chr11: 68,683,779-68,691,175

IGFBP4

insulin like growth factor binding protein 4

3487

P22692

chr17: 40,443,461-40,457,731

PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

5742

P23219

chr9: 122,370,530-122,395,703

SP100

SP100 nuclear antigen

6672

P23497

chr2: 230,415,942-230,544,090

CXCR2

chemokine (C-X-C motif) receptor 2

3579

P25025

chr2: 218,125,289-218,137,253

FPR2

formyl peptide receptor 2

2358

P25090

chr19: 51,752,026-51,770,526

PTAFR

platelet-activating factor receptor

5724

P25105

chr1: 28,147,166-28,193,936

F2R

coagulation factor II (thrombin) receptor

2149

P25116

chr5: 76,716,043-76,735,781

FAS

Fas cell surface death receptor

355

P25445

chr10: 88,990,582-89,015,785

PTX3

pentraxin 3

5806

P26022

chr3: 157,436,789-157,443,628

CD27

CD27 molecule

939

P26842

chr12: 6,444,867-6,451,718

AOAH

acyloxyacyl hydrolase

313

P28039

chr7: 36,512,949-36,724,549

TNFRSF8

tumor necrosis factor receptor superfamily member 8

943

P28908

chr1: 12,063,377-12,144,207

CD40LG

CD40 ligand

959

P29965

chrX: 136,648,193-136,660,390

ADORA1

adenosine A1 receptor

134

P30542

chr1: 203,090,654-203,167,405

AKT1

v-akt murine thymoma viral oncogene homolog 1

207

P31749

chr14: 104,769,349-104,795,751

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

5743

P35354

chr1: 186,671,791-186,680,427

HRH1

histamine receptor H1

3269

P35367

chr3: 11,137,093-11,263,557

CHI3L1

chitinase 3 like 1

1116

P36222

chr1: 203,178,931-203,186,749

LTBR

lymphotoxin beta receptor

4055

P36941

chr12: 6,375,045-6,391,571

LIPA

lipase A, lysosomal acid, cholesterol esterase

3988

P38571

chr10: 89,213,569-89,414,557

BCL6

B-cell CLL/lymphoma 6

604

P41182

chr3: 187,721,377-187,745,727

CXCL5

chemokine (C-X-C motif) ligand 5

6374

P42830

chr4: 73,995,642-73,998,779

PTGFR

prostaglandin F receptor (FP)

5737

P43088

chr1: 78,303,884-78,539,749

PTGER3

prostaglandin E receptor 3

5733

P43115

chr1: 70,852,353-71,047,808

PTGER2

prostaglandin E receptor 2

5732

P43116

chr14: 52,314,305-52,328,606

SYK

spleen tyrosine kinase

6850

P43405

chr9: 90,801,787-90,898,549

CXCL12

chemokine (C-X-C motif) ligand 12

6387

P48061

chr10: 44,370,165-44,386,493

PIK3CG

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

5294

P48736

chr7: 106,865,278-106,907,145

CD97

adhesion G protein-coupled receptor E5

976

P48960

chr19: 14,380,501-14,408,725

MAPKAPK2

mitogen-activated protein kinase-activated protein kinase 2

9261

P49137

chr1: 206,684,944-206,734,283

SLC11A1

solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1

6556

P49279

chr2: 218,382,029-218,396,894

CASP4

caspase 4

837

P49662

chr11: 104,942,866-104,969,436

AGTR2

angiotensin II receptor, type 2

186

P50052

chrX: 116,170,722-116,174,972

NDST1

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

3340

P52848

chr5: 150,485,818-150,558,211

F2RL1

coagulation factor II (thrombin) receptor-like 1

2150

P55085

chr5: 76,818,933-76,835,315

HDAC4

histone deacetylase 4

9759

P56524

chr2: 239,048,168-239,401,654

TIRAP

toll-interleukin 1 receptor (TIR) domain containing adaptor protein

114609

P58753

chr11: 126,283,065-126,298,845

PLP1

proteolipid protein 1

5354

P60201

chrX: 103,773,718-103,792,619

CXCR4

chemokine (C-X-C motif) receptor 4

7852

P61073

chr2: 136,114,349-136,118,165

LYZ

lysozyme

4069

P61626

chr12: 69,348,341-69,354,234

RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

5879

P63000

chr7: 6,374,523-6,403,977

ADAM8

ADAM metallopeptidase domain 8

101

P78325

chr10: 133,262,403-133,276,868

OLR1

oxidized low density lipoprotein (lectin-like) receptor 1

4973

P78380

chr12: 10,158,301-10,172,138

ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

1999

P78545

chr1: 202,007,945-202,017,188

CCL20

chemokine (C-C motif) ligand 20

6364

P78556

chr2: 227,813,842-227,817,564

CCL8

chemokine (C-C motif) ligand 8

6355

P80075

chr17: 34,319,036-34,321,402

CXCL6

chemokine (C-X-C motif) ligand 6

6372

P80162

chr4: 73,836,497-73,849,064

TNFAIP6

TNF alpha induced protein 6

7130

P98066

chr2: 151,357,592-151,380,048

RELB

v-rel avian reticuloendotheliosis viral oncogene homolog B

5971

Q01201

chr19: 45,001,430-45,038,198

RELA

v-rel avian reticuloendotheliosis viral oncogene homolog A

5970

Q04206

chr11: 65,653,596-65,663,094

PRKCQ

protein kinase C, theta

5588

Q04759

chr10: 6,427,143-6,580,301

REL

v-rel avian reticuloendotheliosis viral oncogene homolog

5966

Q04864

chr2: 60,881,521-60,931,610

AOX1

aldehyde oxidase 1

316

Q06278

chr2: 200,585,868-200,677,064

IL10RB

interleukin 10 receptor subunit beta

3588

Q08334

chr21: 33,266,358-33,310,187

PTGDR

prostaglandin D2 receptor (DP)

5729

Q13258

chr14: 52,267,713-52,276,724

NMI

N-myc and STAT interactor

9111

Q13287

chr2: 151,270,465-151,290,057

IL18

interleukin 18

3606

Q14116

chr11: 112,143,251-112,164,117

NFE2L1

nuclear factor, erythroid 2 like 1

4779

Q14494

chr17: 48,048,329-48,061,487

NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

4776

Q14934

chr14: 24,365,673-24,379,604

PRKD1

protein kinase D1

5587

Q15139

chr14: 29,576,479-30,191,898

TLR1

toll-like receptor 1

7096

Q15399

chr4: 38,790,677-38,856,817

SMAD1

SMAD family member 1

4086

Q15797

chr4: 145,481,194-145,558,079

SCN9A

sodium channel, voltage gated, type IX alpha subunit

6335

Q15858

chr2: 166,195,185-166,375,993

IFI16

interferon, gamma-inducible protein 16

3428

Q16666

chr1: 158,999,968-159,055,155

AOC3

amine oxidase, copper containing 3

8639

Q16853

chr17: 42,851,184-42,858,130

CDO1

cysteine dioxygenase type 1

1036

Q16878

chr5: 115,804,733-115,816,954

THEMIS2

thymocyte selection associated family member 2

9473

Q5TEJ8

chr1: 27,872,543-27,886,685

NFRKB

nuclear factor related to kappaB binding protein

4798

Q6P4R8

chr11: 129,863,636-129,895,590

IL34

interleukin 34

146433

Q6ZMJ4

chr16: 70,579,895-70,660,682

PXK

PX domain containing serine/threonine kinase

54899

Q7Z7A4

chr3: 58,332,880-58,426,126

CAMK1D

calcium/calmodulin dependent protein kinase ID

57118

Q8IU85

chr10: 12,349,482-12,835,545

SCUBE1

signal peptide, CUB domain, EGF-like 1

80274

Q8IWY4

chr22: 43,197,283-43,343,388

AFAP1L2

actin filament associated protein 1 like 2

84632

Q8N4X5

chr10: 114,294,824-114,404,756

CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

10164

Q8NCG5

chr16: 71,525,233-71,538,746

ABCF1

ATP binding cassette subfamily F member 1

23

Q8NE71

chr6: 30,571,376-30,597,179

BLNK

B-cell linker

29760

Q8WV28

chr10: 96,191,702-96,271,587

TNFRSF25

tumor necrosis factor receptor superfamily member 25

8718

Q93038

chr1: 6,461,151-6,466,195

ITCH

itchy E3 ubiquitin protein ligase

83737

Q96J02

chr20: 34,363,235-34,511,393

NR1H4

nuclear receptor subfamily 1 group H member 4

9971

Q96RI1

chr12: 100,473,708-100,564,413

S1PR3

sphingosine-1-phosphate receptor 3

1903

Q99500

chr9: 88,991,447-89,005,010

GPER1

G protein-coupled estrogen receptor 1

2852

Q99527

chr7: 1,082,208-1,093,815

MGLL

monoglyceride lipase

11343

Q99685

chr3: 127,689,062-127,823,250

RARRES2

retinoic acid receptor responder (tazarotene induced) 2

5919

Q99969

chr7: 150,338,317-150,341,674

LXN

latexin

56925

Q9BS40

chr3: 158,645,822-158,672,693

CLEC7A

C-type lectin domain family 7 member A

64581

Q9BXN2

chr12: 10,116,777-10,130,258

NFKBIZ

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

64332

Q9BYH8

chr3: 101,827,991-101,861,022

SIGLEC1

sialic acid binding Ig-like lectin 1, sialoadhesin

6614

Q9BZZ2

chr20: 3,686,970-3,707,128

TOLLIP

toll interacting protein

54472

Q9H0E2

chr11: 1,274,371-1,309,654

PLGRKT

plasminogen receptor, C-terminal lysine transmembrane protein

55848

Q9HBL7

chr9: 5,357,973-5,437,878

MMP25

matrix metallopeptidase 25

64386

Q9NPA2

chr16: 3,046,681-3,060,726

IL1RAP

interleukin 1 receptor accessory protein

3556

Q9NPH3

chr3: 190,514,051-190,659,750

NOX4

NADPH oxidase 4

50507

Q9NPH5

chr11: 89,324,356-89,498,187

CYP26B1

cytochrome P450 family 26 subfamily B member 1

56603

Q9NR63

chr2: 72,129,238-72,148,038

STAB1

stabilin 1

23166

Q9NY15

chr3: 52,495,338-52,524,495

SPHK1

sphingosine kinase 1

8877

Q9NYA1

chr17: 76,376,584-76,387,860

IL37

interleukin 37

27178

Q9NZH6

chr2: 112,912,971-112,918,882

TBK1

TANK-binding kinase 1

29110

Q9UHD2

chr12: 64,451,880-64,502,108

ZNF580

zinc finger protein 580

51157

Q9UK33

chr19: 55,635,016-55,643,469

HDAC9

histone deacetylase 9

9734

Q9UKV0

chr7: 18,086,949-19,002,416

PYCARD

PYD and CARD domain containing

29108

Q9ULZ3

chr16: 31,201,485-31,203,450

PLA2G4C

phospholipase A2 group IVC

8605

Q9UP65

chr19: 48,047,843-48,110,817

HDAC5

histone deacetylase 5

10014

Q9UQL6

chr17: 44,076,746-44,123,702

PLAA

phospholipase A2-activating protein

9373

Q9Y263

chr9: 26,904,083-26,947,463

CHST2

carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2

9435

Q9Y4C5

chr3: 143,119,331-143,124,014

F11R

F11 receptor

50848

Q9Y624

chr1: 160,995,211-161,021,348

TNFRSF11A

tumor necrosis factor receptor superfamily member 11a

8792

Q9Y6Q6

chr18: 62,325,287-62,391,292