GO ID | GO:0006954 |
Ontology | BP |
GO Term | inflammatory response |
Definition | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
---|---|---|---|---|
TLR4 |
toll-like receptor 4 |
7099 |
O00206 |
chr9: 117,704,332-117,716,871 |
TNFRSF11B |
tumor necrosis factor receptor superfamily member 11b |
4982 |
O00300 |
chr8: 118,923,557-118,952,200 |
PIK3CD |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
5293 |
O00329 |
chr1: 9,651,732-9,729,114 |
TNFRSF10C |
tumor necrosis factor receptor superfamily member 10c |
8794 |
O14798 |
chr8: 23,084,355-23,117,437 |
TLR3 |
toll-like receptor 3 |
7098 |
O15455 |
chr4: 186,069,152-186,088,069 |
IRAK2 |
interleukin 1 receptor associated kinase 2 |
3656 |
O43187 |
chr3: 10,164,865-10,243,743 |
RIPK2 |
receptor interacting serine/threonine kinase 2 |
8767 |
O43353 |
chr8: 89,757,747-89,791,063 |
CD5L |
CD5 molecule like |
922 |
O43866 |
chr1: 157,830,914-157,898,256 |
LY75 |
lymphocyte antigen 75 |
4065 |
O60449 |
chr2: 159,803,355-159,904,749 |
TPST1 |
tyrosylprotein sulfotransferase 1 |
8460 |
O60507 |
chr7: 66,205,199-66,420,543 |
TLR5 |
toll-like receptor 5 |
7100 |
O60602 |
chr1: 223,109,406-223,143,282 |
TLR2 |
toll-like receptor 2 |
7097 |
O60603 |
chr4: 153,701,500-153,705,699 |
TSPAN2 |
tetraspanin 2 |
10100 |
O60636 |
chr1: 115,048,011-115,089,500 |
SEMA7A |
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
8482 |
O75326 |
chr15: 74,409,289-74,434,467 |
GPR32 |
G protein-coupled receptor 32 |
2854 |
O75388 |
chr19: 50,770,464-50,771,732 |
TNFRSF21 |
tumor necrosis factor receptor superfamily member 21 |
27242 |
O75509 |
chr6: 47,231,532-47,309,905 |
RPS6KA5 |
ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
9252 |
O75582 |
chr14: 90,847,862-91,060,636 |
TUSC2 |
tumor suppressor candidate 2 |
11334 |
O75896 |
chr3: 50,320,027-50,328,251 |
VNN1 |
vanin 1 |
8876 |
O95497 |
chr6: 132,681,590-132,714,049 |
SERPINA3 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
12 |
P01011 |
chr14: 94,612,377-94,624,055 |
C3 |
complement component 3 |
718 |
P01024 |
chr19: 6,677,704-6,730,562 |
KNG1 |
kininogen 1 |
3827 |
P01042 |
chr3: 186,717,276-186,743,954 |
FOS |
FBJ murine osteosarcoma viral oncogene homolog |
2353 |
P01100 |
chr14: 75,278,774-75,282,230 |
TGFB1 |
transforming growth factor beta 1 |
7040 |
P01137 |
chr19: 41,301,587-41,353,911 |
TNF |
tumor necrosis factor |
7124 |
P01375 |
chr6: 31,575,567-31,578,336 |
IL1A |
interleukin 1 alpha |
3552 |
P01583 |
chr2: 112,773,915-112,784,590 |
IL1B |
interleukin 1 beta |
3553 |
P01584 |
chr2: 112,829,751-112,836,903 |
CRP |
C-reactive protein, pentraxin-related |
1401 |
P02741 |
chr1: 159,712,289-159,714,589 |
ORM1 |
orosomucoid 1 |
5004 |
P02763 |
chr9: 114,323,056-114,326,475 |
PPBP |
pro-platelet basic protein |
5473 |
P02775 |
chr4: 73,987,038-73,988,197 |
PF4 |
platelet factor 4 |
5196 |
P02776 |
chr4: 73,981,077-73,982,124 |
ANXA1 |
annexin A1 |
301 |
P04083 |
chr9: 73,151,757-73,170,393 |
CYBB |
cytochrome b-245, beta polypeptide |
1536 |
P04839 |
chrX: 37,780,011-37,813,461 |
ITGB2 |
integrin subunit beta 2 |
3689 |
P05107 |
chr21: 44,885,953-44,931,989 |
S100A8 |
S100 calcium binding protein A8 |
6279 |
P05109 |
chr1: 153,390,032-153,391,188 |
IL6 |
interleukin 6 |
3569 |
P05231 |
chr7: 22,725,884-22,732,002 |
S100A9 |
S100 calcium binding protein A9 |
6280 |
P06702 |
chr1: 153,357,854-153,361,027 |
CSF1R |
colony stimulating factor 1 receptor |
1436 |
P07333 |
chr5: 150,053,291-150,113,372 |
LYN |
LYN proto-oncogene, Src family tyrosine kinase |
4067 |
P07948 |
chr8: 55,879,813-56,014,168 |
THBS1 |
thrombospondin 1 |
7057 |
P07996 |
chr15: 39,581,079-39,599,466 |
NGFR |
nerve growth factor receptor |
4804 |
P08138 |
chr17: 49,495,293-49,515,017 |
CD14 |
CD14 molecule |
929 |
P08571 |
chr5: 140,631,728-140,633,701 |
KRT16 |
keratin 16, type I |
3868 |
P08779 |
chr17: 41,609,778-41,615,899 |
CXCL1 |
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
2919 |
P09341 |
chr4: 73,869,393-73,871,242 |
HMGB1 |
high mobility group box 1 |
3146 |
P09429 |
chr13: 30,456,704-30,617,597 |
C4A |
complement component 4A (Rodgers blood group) |
720 |
P0C0L4 |
chr6: 31,982,024-32,002,681 |
C4B |
complement component 4B (Chido blood group) |
721 |
P0C0L5 |
chr6: 32,014,762-32,035,418 |
CXCL8 |
chemokine (C-X-C motif) ligand 8 |
3576 |
P10145 |
chr4: 73,740,506-73,743,716 |
CCL3 |
chemokine (C-C motif) ligand 3 |
6348 |
P10147 |
chr17: 36,088,256-36,090,169 |
SPP1 |
secreted phosphoprotein 1 |
6696 |
P10451 |
chr4: 87,975,650-87,983,426 |
KIT |
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
3815 |
P10721 |
chr4: 54,657,918-54,740,715 |
BMP2 |
bone morphogenetic protein 2 |
650 |
P12643 |
chr20: 6,767,664-6,780,280 |
CCL4 |
chemokine (C-C motif) ligand 4 |
6351 |
P13236 |
chr17: 36,103,590-36,105,621 |
CCL2 |
chemokine (C-C motif) ligand 2 |
6347 |
P13500 |
chr17: 34,255,218-34,257,203 |
CCL5 |
chemokine (C-C motif) ligand 5 |
6352 |
P13501 |
chr17: 35,871,491-35,880,793 |
SCG2 |
secretogranin II |
7857 |
P13521 |
chr2: 223,596,940-223,602,503 |
MIF |
macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
4282 |
P14174 |
chr22: 23,894,004-23,895,227 |
ALOX15 |
arachidonate 15-lipoxygenase |
246 |
P16050 |
chr17: 4,630,902-4,642,294 |
SELE |
selectin E |
6401 |
P16581 |
chr1: 169,722,641-169,764,705 |
CEBPB |
CCAAT/enhancer binding protein (C/EBP), beta |
1051 |
P17676 |
chr20: 50,190,734-50,192,689 |
SDC1 |
syndecan 1 |
6382 |
P18827 |
chr2: 20,200,797-20,225,433 |
NFKB1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
4790 |
P19838 |
chr4: 102,501,329-102,617,302 |
CXCL2 |
chemokine (C-X-C motif) ligand 2 |
2920 |
P19875 |
chr4: 74,097,035-74,099,293 |
TNFRSF1B |
tumor necrosis factor receptor superfamily member 1B |
7133 |
P20333 |
chr1: 12,167,003-12,209,228 |
FPR1 |
formyl peptide receptor 1 |
2357 |
P21462 |
chr19: 51,745,172-51,804,110 |
TNFAIP3 |
TNF alpha induced protein 3 |
7128 |
P21580 |
chr6: 137,867,188-137,883,312 |
C5AR1 |
complement component 5a receptor 1 |
728 |
P21730 |
chr19: 47,290,023-47,322,066 |
BMP6 |
bone morphogenetic protein 6 |
654 |
P22004 |
chr6: 7,726,797-7,881,422 |
IL10 |
interleukin 10 |
3586 |
P22301 |
chr1: 206,767,602-206,772,494 |
GAL |
galanin/GMAP prepropeptide |
51083 |
P22466 |
chr11: 68,683,779-68,691,175 |
IGFBP4 |
insulin like growth factor binding protein 4 |
3487 |
P22692 |
chr17: 40,443,461-40,457,731 |
PTGS1 |
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
5742 |
P23219 |
chr9: 122,370,530-122,395,703 |
SP100 |
SP100 nuclear antigen |
6672 |
P23497 |
chr2: 230,415,942-230,544,090 |
CXCR2 |
chemokine (C-X-C motif) receptor 2 |
3579 |
P25025 |
chr2: 218,125,289-218,137,253 |
FPR2 |
formyl peptide receptor 2 |
2358 |
P25090 |
chr19: 51,752,026-51,770,526 |
PTAFR |
platelet-activating factor receptor |
5724 |
P25105 |
chr1: 28,147,166-28,193,936 |
F2R |
coagulation factor II (thrombin) receptor |
2149 |
P25116 |
chr5: 76,716,043-76,735,781 |
FAS |
Fas cell surface death receptor |
355 |
P25445 |
chr10: 88,990,582-89,015,785 |
PTX3 |
pentraxin 3 |
5806 |
P26022 |
chr3: 157,436,789-157,443,628 |
CD27 |
CD27 molecule |
939 |
P26842 |
chr12: 6,444,867-6,451,718 |
AOAH |
acyloxyacyl hydrolase |
313 |
P28039 |
chr7: 36,512,949-36,724,549 |
TNFRSF8 |
tumor necrosis factor receptor superfamily member 8 |
943 |
P28908 |
chr1: 12,063,377-12,144,207 |
CD40LG |
CD40 ligand |
959 |
P29965 |
chrX: 136,648,193-136,660,390 |
ADORA1 |
adenosine A1 receptor |
134 |
P30542 |
chr1: 203,090,654-203,167,405 |
AKT1 |
v-akt murine thymoma viral oncogene homolog 1 |
207 |
P31749 |
chr14: 104,769,349-104,795,751 |
PTGS2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
5743 |
P35354 |
chr1: 186,671,791-186,680,427 |
HRH1 |
histamine receptor H1 |
3269 |
P35367 |
chr3: 11,137,093-11,263,557 |
CHI3L1 |
chitinase 3 like 1 |
1116 |
P36222 |
chr1: 203,178,931-203,186,749 |
LTBR |
lymphotoxin beta receptor |
4055 |
P36941 |
chr12: 6,375,045-6,391,571 |
LIPA |
lipase A, lysosomal acid, cholesterol esterase |
3988 |
P38571 |
chr10: 89,213,569-89,414,557 |
BCL6 |
B-cell CLL/lymphoma 6 |
604 |
P41182 |
chr3: 187,721,377-187,745,727 |
CXCL5 |
chemokine (C-X-C motif) ligand 5 |
6374 |
P42830 |
chr4: 73,995,642-73,998,779 |
PTGFR |
prostaglandin F receptor (FP) |
5737 |
P43088 |
chr1: 78,303,884-78,539,749 |
PTGER3 |
prostaglandin E receptor 3 |
5733 |
P43115 |
chr1: 70,852,353-71,047,808 |
PTGER2 |
prostaglandin E receptor 2 |
5732 |
P43116 |
chr14: 52,314,305-52,328,606 |
SYK |
spleen tyrosine kinase |
6850 |
P43405 |
chr9: 90,801,787-90,898,549 |
CXCL12 |
chemokine (C-X-C motif) ligand 12 |
6387 |
P48061 |
chr10: 44,370,165-44,386,493 |
PIK3CG |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
5294 |
P48736 |
chr7: 106,865,278-106,907,145 |
CD97 |
adhesion G protein-coupled receptor E5 |
976 |
P48960 |
chr19: 14,380,501-14,408,725 |
MAPKAPK2 |
mitogen-activated protein kinase-activated protein kinase 2 |
9261 |
P49137 |
chr1: 206,684,944-206,734,283 |
SLC11A1 |
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
6556 |
P49279 |
chr2: 218,382,029-218,396,894 |
CASP4 |
caspase 4 |
837 |
P49662 |
chr11: 104,942,866-104,969,436 |
AGTR2 |
angiotensin II receptor, type 2 |
186 |
P50052 |
chrX: 116,170,722-116,174,972 |
NDST1 |
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
3340 |
P52848 |
chr5: 150,485,818-150,558,211 |
F2RL1 |
coagulation factor II (thrombin) receptor-like 1 |
2150 |
P55085 |
chr5: 76,818,933-76,835,315 |
HDAC4 |
histone deacetylase 4 |
9759 |
P56524 |
chr2: 239,048,168-239,401,654 |
TIRAP |
toll-interleukin 1 receptor (TIR) domain containing adaptor protein |
114609 |
P58753 |
chr11: 126,283,065-126,298,845 |
PLP1 |
proteolipid protein 1 |
5354 |
P60201 |
chrX: 103,773,718-103,792,619 |
CXCR4 |
chemokine (C-X-C motif) receptor 4 |
7852 |
P61073 |
chr2: 136,114,349-136,118,165 |
LYZ |
lysozyme |
4069 |
P61626 |
chr12: 69,348,341-69,354,234 |
RAC1 |
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
5879 |
P63000 |
chr7: 6,374,523-6,403,977 |
ADAM8 |
ADAM metallopeptidase domain 8 |
101 |
P78325 |
chr10: 133,262,403-133,276,868 |
OLR1 |
oxidized low density lipoprotein (lectin-like) receptor 1 |
4973 |
P78380 |
chr12: 10,158,301-10,172,138 |
ELF3 |
E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
1999 |
P78545 |
chr1: 202,007,945-202,017,188 |
CCL20 |
chemokine (C-C motif) ligand 20 |
6364 |
P78556 |
chr2: 227,813,842-227,817,564 |
CCL8 |
chemokine (C-C motif) ligand 8 |
6355 |
P80075 |
chr17: 34,319,036-34,321,402 |
CXCL6 |
chemokine (C-X-C motif) ligand 6 |
6372 |
P80162 |
chr4: 73,836,497-73,849,064 |
TNFAIP6 |
TNF alpha induced protein 6 |
7130 |
P98066 |
chr2: 151,357,592-151,380,048 |
RELB |
v-rel avian reticuloendotheliosis viral oncogene homolog B |
5971 |
Q01201 |
chr19: 45,001,430-45,038,198 |
RELA |
v-rel avian reticuloendotheliosis viral oncogene homolog A |
5970 |
Q04206 |
chr11: 65,653,596-65,663,094 |
PRKCQ |
protein kinase C, theta |
5588 |
Q04759 |
chr10: 6,427,143-6,580,301 |
REL |
v-rel avian reticuloendotheliosis viral oncogene homolog |
5966 |
Q04864 |
chr2: 60,881,521-60,931,610 |
AOX1 |
aldehyde oxidase 1 |
316 |
Q06278 |
chr2: 200,585,868-200,677,064 |
IL10RB |
interleukin 10 receptor subunit beta |
3588 |
Q08334 |
chr21: 33,266,358-33,310,187 |
PTGDR |
prostaglandin D2 receptor (DP) |
5729 |
Q13258 |
chr14: 52,267,713-52,276,724 |
NMI |
N-myc and STAT interactor |
9111 |
Q13287 |
chr2: 151,270,465-151,290,057 |
IL18 |
interleukin 18 |
3606 |
Q14116 |
chr11: 112,143,251-112,164,117 |
NFE2L1 |
nuclear factor, erythroid 2 like 1 |
4779 |
Q14494 |
chr17: 48,048,329-48,061,487 |
NFATC4 |
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
4776 |
Q14934 |
chr14: 24,365,673-24,379,604 |
PRKD1 |
protein kinase D1 |
5587 |
Q15139 |
chr14: 29,576,479-30,191,898 |
TLR1 |
toll-like receptor 1 |
7096 |
Q15399 |
chr4: 38,790,677-38,856,817 |
SMAD1 |
SMAD family member 1 |
4086 |
Q15797 |
chr4: 145,481,194-145,558,079 |
SCN9A |
sodium channel, voltage gated, type IX alpha subunit |
6335 |
Q15858 |
chr2: 166,195,185-166,375,993 |
IFI16 |
interferon, gamma-inducible protein 16 |
3428 |
Q16666 |
chr1: 158,999,968-159,055,155 |
AOC3 |
amine oxidase, copper containing 3 |
8639 |
Q16853 |
chr17: 42,851,184-42,858,130 |
CDO1 |
cysteine dioxygenase type 1 |
1036 |
Q16878 |
chr5: 115,804,733-115,816,954 |
THEMIS2 |
thymocyte selection associated family member 2 |
9473 |
Q5TEJ8 |
chr1: 27,872,543-27,886,685 |
NFRKB |
nuclear factor related to kappaB binding protein |
4798 |
Q6P4R8 |
chr11: 129,863,636-129,895,590 |
IL34 |
interleukin 34 |
146433 |
Q6ZMJ4 |
chr16: 70,579,895-70,660,682 |
PXK |
PX domain containing serine/threonine kinase |
54899 |
Q7Z7A4 |
chr3: 58,332,880-58,426,126 |
CAMK1D |
calcium/calmodulin dependent protein kinase ID |
57118 |
Q8IU85 |
chr10: 12,349,482-12,835,545 |
SCUBE1 |
signal peptide, CUB domain, EGF-like 1 |
80274 |
Q8IWY4 |
chr22: 43,197,283-43,343,388 |
AFAP1L2 |
actin filament associated protein 1 like 2 |
84632 |
Q8N4X5 |
chr10: 114,294,824-114,404,756 |
CHST4 |
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
10164 |
Q8NCG5 |
chr16: 71,525,233-71,538,746 |
ABCF1 |
ATP binding cassette subfamily F member 1 |
23 |
Q8NE71 |
chr6: 30,571,376-30,597,179 |
BLNK |
B-cell linker |
29760 |
Q8WV28 |
chr10: 96,191,702-96,271,587 |
TNFRSF25 |
tumor necrosis factor receptor superfamily member 25 |
8718 |
Q93038 |
chr1: 6,461,151-6,466,195 |
ITCH |
itchy E3 ubiquitin protein ligase |
83737 |
Q96J02 |
chr20: 34,363,235-34,511,393 |
NR1H4 |
nuclear receptor subfamily 1 group H member 4 |
9971 |
Q96RI1 |
chr12: 100,473,708-100,564,413 |
S1PR3 |
sphingosine-1-phosphate receptor 3 |
1903 |
Q99500 |
chr9: 88,991,447-89,005,010 |
GPER1 |
G protein-coupled estrogen receptor 1 |
2852 |
Q99527 |
chr7: 1,082,208-1,093,815 |
MGLL |
monoglyceride lipase |
11343 |
Q99685 |
chr3: 127,689,062-127,823,250 |
RARRES2 |
retinoic acid receptor responder (tazarotene induced) 2 |
5919 |
Q99969 |
chr7: 150,338,317-150,341,674 |
LXN |
latexin |
56925 |
Q9BS40 |
chr3: 158,645,822-158,672,693 |
CLEC7A |
C-type lectin domain family 7 member A |
64581 |
Q9BXN2 |
chr12: 10,116,777-10,130,258 |
NFKBIZ |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
64332 |
Q9BYH8 |
chr3: 101,827,991-101,861,022 |
SIGLEC1 |
sialic acid binding Ig-like lectin 1, sialoadhesin |
6614 |
Q9BZZ2 |
chr20: 3,686,970-3,707,128 |
TOLLIP |
toll interacting protein |
54472 |
Q9H0E2 |
chr11: 1,274,371-1,309,654 |
PLGRKT |
plasminogen receptor, C-terminal lysine transmembrane protein |
55848 |
Q9HBL7 |
chr9: 5,357,973-5,437,878 |
MMP25 |
matrix metallopeptidase 25 |
64386 |
Q9NPA2 |
chr16: 3,046,681-3,060,726 |
IL1RAP |
interleukin 1 receptor accessory protein |
3556 |
Q9NPH3 |
chr3: 190,514,051-190,659,750 |
NOX4 |
NADPH oxidase 4 |
50507 |
Q9NPH5 |
chr11: 89,324,356-89,498,187 |
CYP26B1 |
cytochrome P450 family 26 subfamily B member 1 |
56603 |
Q9NR63 |
chr2: 72,129,238-72,148,038 |
STAB1 |
stabilin 1 |
23166 |
Q9NY15 |
chr3: 52,495,338-52,524,495 |
SPHK1 |
sphingosine kinase 1 |
8877 |
Q9NYA1 |
chr17: 76,376,584-76,387,860 |
IL37 |
interleukin 37 |
27178 |
Q9NZH6 |
chr2: 112,912,971-112,918,882 |
TBK1 |
TANK-binding kinase 1 |
29110 |
Q9UHD2 |
chr12: 64,451,880-64,502,108 |
ZNF580 |
zinc finger protein 580 |
51157 |
Q9UK33 |
chr19: 55,635,016-55,643,469 |
HDAC9 |
histone deacetylase 9 |
9734 |
Q9UKV0 |
chr7: 18,086,949-19,002,416 |
PYCARD |
PYD and CARD domain containing |
29108 |
Q9ULZ3 |
chr16: 31,201,485-31,203,450 |
PLA2G4C |
phospholipase A2 group IVC |
8605 |
Q9UP65 |
chr19: 48,047,843-48,110,817 |
HDAC5 |
histone deacetylase 5 |
10014 |
Q9UQL6 |
chr17: 44,076,746-44,123,702 |
PLAA |
phospholipase A2-activating protein |
9373 |
Q9Y263 |
chr9: 26,904,083-26,947,463 |
CHST2 |
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
9435 |
Q9Y4C5 |
chr3: 143,119,331-143,124,014 |
F11R |
F11 receptor |
50848 |
Q9Y624 |
chr1: 160,995,211-161,021,348 |
TNFRSF11A |
tumor necrosis factor receptor superfamily member 11a |
8792 |
Q9Y6Q6 |
chr18: 62,325,287-62,391,292 |