Gene Ontology Description

GO ID GO:0006283
Ontology BP
GO Term transcription-coupled nucleotide-excision repair
Definition The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

POLR2D

polymerase (RNA) II (DNA directed) polypeptide D

5433

O15514

chr2: 127,843,551-127,858,157

ERCC1

excision repair cross-complementation group 1

2067

P07992

chr19: 45,407,333-45,478,828

UBC

ubiquitin C

7316

P0CG48

chr12: 124,911,604-124,917,368

PCNA

proliferating cell nuclear antigen

5111

P12004

chr20: 5,114,953-5,126,626

ERCC2

excision repair cross-complementation group 2

2068

P18074

chr19: 45,349,837-45,370,918

LIG1

ligase I, DNA, ATP-dependent

3978

P18858

chr19: 48,115,445-48,170,603

POLR2E

polymerase (RNA) II (DNA directed) polypeptide E, 25kDa

5434

P19388

chr19: 1,086,579-1,095,380

XPA

xeroderma pigmentosum, complementation group A

7507

P23025

chr9: 97,674,909-97,697,357

POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

5430

P24928

chr17: 7,484,366-7,514,616

POLD1

polymerase (DNA directed), delta 1, catalytic subunit

5424

P28340

chr19: 50,384,204-50,418,018

POLR2B

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

5431

P30876

chr4: 56,977,722-57,031,168

GTF2H1

general transcription factor IIH subunit 1

2965

P32780

chr11: 18,322,295-18,367,044

RPA3

replication protein A3

6119

P35244

chr7: 7,636,518-7,718,607

RFC4

replication factor C subunit 4

5984

P35249

chr3: 186,789,880-186,807,058

RFC2

replication factor C subunit 2

5982

P35250

chr7: 74,231,499-74,254,458

POLR2I

polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa

5438

P36954

chr19: 36,113,710-36,115,346

RFC5

replication factor C subunit 5

5985

P40937

chr12: 118,013,588-118,033,130

RFC3

replication factor C subunit 3

5983

P40938

chr13: 33,818,049-33,966,558

CDK7

cyclin-dependent kinase 7

1022

P50613

chr5: 69,234,795-69,277,430

POLR2J

polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa

5439

P52435

chr7: 102,473,118-102,478,907

POLR2K

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

5440

P53803

chr8: 100,150,584-100,154,002

POLR2G

polymerase (RNA) II (DNA directed) polypeptide G

5436

P62487

chr11: 62,761,544-62,766,710

POLR2L

polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa

5441

P62875

chr11: 837,356-842,545

RBX1

ring-box 1, E3 ubiquitin protein ligase

9978

P62877

chr22: 40,951,347-40,973,309

RPS27A

ribosomal protein S27a

6233

P62979

chr2: 55,231,903-55,235,853

UBA52

ubiquitin A-52 residue ribosomal protein fusion product 1

7311

P62987

chr19: 18,571,730-18,577,550

EP300

E1A binding protein p300

2033

Q09472

chr22: 41,091,786-41,180,079

CUL4A

cullin 4A

8451

Q13619

chr13: 113,208,193-113,267,108

CUL4B

cullin 4B

8450

Q13620

chrX: 120,524,609-120,575,794

GTF2H2

general transcription factor IIH subunit 2

2966

Q13888

chr5: 71,032,670-71,067,689

POLD3

polymerase (DNA-directed), delta 3, accessory subunit

10714

Q15054

chr11: 74,493,851-74,669,117

COPS6

COP9 signalosome subunit 6

10980

Q7L5N1

chr7: 100,088,954-100,092,200

GTF2H4

general transcription factor IIH subunit 4

2968

Q92759

chr6: 30,908,184-30,914,106

ERCC4

excision repair cross-complementation group 4

2072

Q92889

chr16: 13,920,157-13,952,345

COPS8

COP9 signalosome subunit 8

10920

Q99627

chr2: 237,085,312-237,100,466

COPS7B

COP9 signalosome subunit 7B

64708

Q9H9Q2

chr2: 231,781,671-231,809,254

POLD4

polymerase (DNA-directed), delta 4, accessory subunit

57804

Q9HCU8

chr11: 67,350,777-67,356,972

POLK

polymerase (DNA directed) kappa

51426

Q9UBT6

chr5: 75,511,756-75,601,144

PRPF19

pre-mRNA processing factor 19

27339

Q9UMS4

chr11: 60,890,730-60,906,588

PPIE

peptidylprolyl isomerase E (cyclophilin E)

10450

Q9UNP9

chr1: 39,692,182-39,763,914