GO ID | GO:0005578 |
Ontology | CC |
GO Term | proteinaceous extracellular matrix |
Definition | A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus. |
Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
---|---|---|---|---|
TNFRSF11B |
tumor necrosis factor receptor superfamily member 11b |
4982 |
O00300 |
chr8: 118,923,557-118,952,200 |
MATN2 |
matrilin 2 |
4147 |
O00339 |
chr8: 97,868,840-98,036,716 |
CHL1 |
cell adhesion molecule L1-like |
10752 |
O00533 |
chr3: 196,596-409,417 |
CYR61 |
cysteine-rich, angiogenic inducer, 61 |
3491 |
O00622 |
chr1: 85,580,761-85,583,962 |
NCAN |
neurocan |
1463 |
O14594 |
chr19: 19,211,973-19,252,233 |
FLRT2 |
fibronectin leucine rich transmembrane protein 2 |
23768 |
O43155 |
chr14: 85,530,144-85,654,426 |
COCH |
cochlin |
1690 |
O43405 |
chr14: 30,874,514-30,895,065 |
CILP |
cartilage intermediate layer protein |
8483 |
O75339 |
chr15: 65,194,758-65,211,488 |
TECTA |
tectorin alpha |
7007 |
O75443 |
chr11: 121,101,173-121,191,493 |
GPC4 |
glypican 4 |
2239 |
O75487 |
chrX: 133,300,103-133,415,490 |
CRTAP |
cartilage associated protein |
10491 |
O75718 |
chr3: 33,113,979-33,147,773 |
WISP2 |
WNT1 inducible signaling pathway protein 2 |
8839 |
O76076 |
chr20: 44,714,844-44,728,509 |
ECM2 |
extracellular matrix protein 2, female organ and adipocyte specific |
1842 |
O94769 |
chr9: 92,493,554-92,536,655 |
SLIT2 |
slit guidance ligand 2 |
9353 |
O94813 |
chr4: 20,253,260-20,620,561 |
WISP1 |
WNT1 inducible signaling pathway protein 1 |
8840 |
O95388 |
chr8: 133,191,039-133,230,344 |
PAPLN |
papilin, proteoglycan-like sulfated glycoprotein |
89932 |
O95428 |
chr14: 73,237,497-73,274,640 |
SERPINA1 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
5265 |
P01009 |
chr14: 94,376,747-94,390,693 |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
7076 |
P01033 |
chrX: 47,582,313-47,586,789 |
TGFB1 |
transforming growth factor beta 1 |
7040 |
P01137 |
chr19: 41,301,587-41,353,911 |
MMP1 |
matrix metallopeptidase 1 |
4312 |
P03956 |
chr11: 102,789,920-102,798,160 |
VWF |
von Willebrand factor |
7450 |
P04275 |
chr12: 5,948,874-6,124,770 |
ALPL |
alkaline phosphatase, liver/bone/kidney |
249 |
P05186 |
chr1: 21,509,372-21,578,412 |
MMP2 |
matrix metallopeptidase 2 |
4313 |
P08253 |
chr16: 55,389,700-55,506,691 |
MGP |
matrix Gla protein |
4256 |
P08493 |
chr12: 14,881,181-14,885,926 |
MMP10 |
matrix metallopeptidase 10 |
4319 |
P09238 |
chr11: 102,770,503-102,780,628 |
LGALS1 |
lectin, galactoside-binding, soluble, 1 |
3956 |
P09382 |
chr22: 37,675,608-37,679,806 |
WNT2 |
wingless-type MMTV integration site family member 2 |
7472 |
P09544 |
chr7: 117,276,631-117,323,289 |
HAPLN1 |
hyaluronan and proteoglycan link protein 1 |
1404 |
P10915 |
chr5: 83,637,805-83,721,613 |
COL6A2 |
collagen, type VI, alpha 2 |
1292 |
P12110 |
chr21: 46,098,097-46,132,849 |
COL6A3 |
collagen, type VI, alpha 3 |
1293 |
P12111 |
chr2: 237,324,003-237,414,375 |
BMP4 |
bone morphogenetic protein 4 |
652 |
P12644 |
chr14: 53,949,736-53,958,761 |
BMP1 |
bone morphogenetic protein 1 |
649 |
P13497 |
chr8: 22,164,736-22,212,326 |
VCAN |
versican |
1462 |
P13611 |
chr5: 83,471,465-83,582,303 |
MMP9 |
matrix metallopeptidase 9 |
4318 |
P14780 |
chr20: 46,008,908-46,016,561 |
VEGFA |
vascular endothelial growth factor A |
7422 |
P15692 |
chr6: 43,770,184-43,786,487 |
TIMP2 |
TIMP metallopeptidase inhibitor 2 |
7077 |
P16035 |
chr17: 78,852,977-78,925,387 |
OGN |
osteoglycin |
4969 |
P20774 |
chr9: 92,383,967-92,404,696 |
COL9A1 |
collagen, type IX, alpha 1 |
1297 |
P20849 |
chr6: 70,215,061-70,303,083 |
ZP3 |
zona pellucida glycoprotein 3 (sperm receptor) |
7784 |
P21754 |
chr7: 76,397,518-76,442,071 |
BGN |
biglycan |
633 |
P21810 |
chrX: 153,494,939-153,509,554 |
TNXB |
tenascin XB |
7148 |
P22105 |
chr6: 32,041,154-32,115,334 |
MMP8 |
matrix metallopeptidase 8 |
4317 |
P22894 |
chr11: 102,711,795-102,727,050 |
FBLN1 |
fibulin 1 |
2192 |
P23142 |
chr22: 45,502,238-45,601,135 |
ANOS1 |
anosmin 1 |
3730 |
P23352 |
chrX: 8,528,874-8,732,186 |
MMP11 |
matrix metallopeptidase 11 |
4320 |
P24347 |
chr22: 23,768,226-23,784,316 |
COL8A2 |
collagen, type VIII, alpha 2 |
1296 |
P25067 |
chr1: 36,095,236-36,125,220 |
CALR |
calreticulin |
811 |
P27797 |
chr19: 12,938,578-12,944,489 |
LOX |
lysyl oxidase |
4015 |
P28300 |
chr5: 122,063,195-122,078,360 |
CTGF |
connective tissue growth factor |
1490 |
P29279 |
chr6: 131,948,176-131,951,373 |
GPC1 |
glypican 1 |
2817 |
P35052 |
chr2: 240,435,671-240,468,078 |
FBN1 |
fibrillin 1 |
2200 |
P35555 |
chr15: 48,408,306-48,645,849 |
TIMP3 |
TIMP metallopeptidase inhibitor 3 |
7078 |
P35625 |
chr22: 32,801,701-32,863,043 |
CHI3L1 |
chitinase 3 like 1 |
1116 |
P36222 |
chr1: 203,178,931-203,186,749 |
WNT5A |
wingless-type MMTV integration site family member 5A |
7474 |
P41221 |
chr3: 55,465,715-55,490,539 |
TFPI2 |
tissue factor pathway inhibitor 2 |
7980 |
P48307 |
chr7: 93,885,397-93,890,991 |
COMP |
cartilage oligomeric matrix protein |
1311 |
P49747 |
chr19: 18,782,773-18,791,314 |
MMP16 |
matrix metallopeptidase 16 |
4325 |
P51512 |
chr8: 88,032,009-88,328,025 |
LUM |
lumican |
4060 |
P51884 |
chr12: 91,102,629-91,111,831 |
CRISP3 |
cysteine-rich secretory protein 3 |
10321 |
P54108 |
chr6: 49,727,384-49,744,437 |
WNT3 |
wingless-type MMTV integration site family member 3 |
7473 |
P56703 |
chr17: 46,762,506-46,833,154 |
ADAMTS12 |
ADAM metallopeptidase with thrombospondin type 1 motif 12 |
81792 |
P58397 |
chr5: 33,523,535-33,892,192 |
ADAMTS20 |
ADAM metallopeptidase with thrombospondin type 1 motif 20 |
80070 |
P59510 |
chr12: 43,353,866-43,551,921 |
ZP1 |
zona pellucida glycoprotein 1 |
22917 |
P60852 |
chr11: 60,867,562-60,875,693 |
GPLD1 |
glycosylphosphatidylinositol specific phospholipase D1 |
2822 |
P80108 |
chr6: 24,424,565-24,495,205 |
FBLN2 |
fibulin 2 |
2199 |
P98095 |
chr3: 13,549,131-13,638,422 |
IL1RL1 |
interleukin 1 receptor-like 1 |
9173 |
Q01638 |
chr2: 102,311,502-102,352,037 |
TGFBR3 |
transforming growth factor beta receptor III |
7049 |
Q03167 |
chr1: 91,680,343-91,906,335 |
COL10A1 |
collagen, type X, alpha 1 |
1300 |
Q03692 |
chr6: 116,118,923-116,158,747 |
COL14A1 |
collagen, type XIV, alpha 1 |
7373 |
Q05707 |
chr8: 120,059,780-120,372,036 |
FMOD |
fibromodulin |
2331 |
Q06828 |
chr1: 203,340,628-203,351,489 |
COL16A1 |
collagen, type XVI, alpha 1 |
1307 |
Q07092 |
chr1: 31,652,247-31,704,319 |
EFEMP1 |
EGF containing fibulin-like extracellular matrix protein 1 |
2202 |
Q12805 |
chr2: 55,865,967-55,924,139 |
DGCR6 |
DiGeorge syndrome critical region gene 6 |
8214 |
Q14129 |
chr22: 18,906,028-18,914,238 |
SPARCL1 |
SPARC like 1 |
8404 |
Q14515 |
chr4: 87,473,335-87,531,061 |
LTBP1 |
latent transforming growth factor beta binding protein 1 |
4052 |
Q14766 |
chr2: 32,946,972-33,399,509 |
POSTN |
periostin, osteoblast specific factor |
10631 |
Q15063 |
chr13: 37,562,583-37,598,844 |
TGFBI |
transforming growth factor beta induced |
7045 |
Q15582 |
chr5: 136,028,895-136,063,818 |
HSD17B12 |
hydroxysteroid (17-beta) dehydrogenase 12 |
51144 |
Q53GQ0 |
chr11: 43,680,558-43,856,617 |
CPZ |
carboxypeptidase Z |
8532 |
Q66K79 |
chr4: 8,592,660-8,619,759 |
OLFML2A |
olfactomedin like 2A |
169611 |
Q68BL7 |
chr9: 124,777,158-124,814,885 |
CCBE1 |
collagen and calcium binding EGF domains 1 |
147372 |
Q6UXH8 |
chr18: 59,430,940-59,697,380 |
GLDN |
gliomedin |
342035 |
Q6ZMI3 |
chr15: 51,341,629-51,408,013 |
FBN3 |
fibrillin 3 |
84467 |
Q75N90 |
chr19: 8,065,402-8,149,846 |
PODN |
podocan |
127435 |
Q7Z5L7 |
chr1: 53,062,052-53,085,502 |
SBSPON |
somatomedin B and thrombospondin type 1 domain containing |
157869 |
Q8IVN8 |
chr8: 73,064,540-73,124,088 |
GPC2 |
glypican 2 |
221914 |
Q8N158 |
chr7: 100,169,606-100,177,372 |
SFRP1 |
secreted frizzled-related protein 1 |
6422 |
Q8N474 |
chr8: 41,261,958-41,309,497 |
NDNF |
neuron-derived neurotrophic factor |
79625 |
Q8TB73 |
chr4: 121,035,613-121,073,021 |
ADAMTS17 |
ADAM metallopeptidase with thrombospondin type 1 motif 17 |
170691 |
Q8TE56 |
chr15: 99,971,589-100,342,005 |
ADAMTS15 |
ADAM metallopeptidase with thrombospondin type 1 motif 15 |
170689 |
Q8TE58 |
chr11: 130,448,974-130,476,641 |
ADAMTS18 |
ADAM metallopeptidase with thrombospondin type 1 motif 18 |
170692 |
Q8TE60 |
chr16: 77,247,813-77,435,114 |
SPOCK2 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
9806 |
Q92563 |
chr10: 72,059,035-72,089,032 |
TNR |
tenascin R |
7143 |
Q92752 |
chr1: 175,315,194-175,743,770 |
GLG1 |
golgi glycoprotein 1 |
2734 |
Q92896 |
chr16: 74,447,427-74,607,144 |
WNT2B |
wingless-type MMTV integration site family member 2B |
7482 |
Q93097 |
chr1: 112,466,541-112,530,165 |
CTHRC1 |
collagen triple helix repeat containing 1 |
115908 |
Q96CG8 |
chr8: 103,371,515-103,382,997 |
BCAN |
brevican |
63827 |
Q96GW7 |
chr1: 156,641,390-156,659,532 |
COL21A1 |
collagen, type XXI, alpha 1 |
81578 |
Q96P44 |
chr6: 56,056,590-56,394,094 |
MUC4 |
mucin 4, cell surface associated |
4585 |
Q99102 |
chr3: 195,746,765-195,812,277 |
MMP19 |
matrix metallopeptidase 19 |
4327 |
Q99542 |
chr12: 55,835,433-55,842,966 |
EPYC |
epiphycan |
1833 |
Q99645 |
chr12: 90,963,679-91,005,026 |
OMD |
osteomodulin |
4958 |
Q99983 |
chr9: 92,414,245-92,424,461 |
SPOCK3 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
50859 |
Q9BQ16 |
chr4: 166,733,384-167,234,796 |
SOST |
sclerostin |
50964 |
Q9BQB4 |
chr17: 43,753,731-43,758,788 |
SPON2 |
spondin 2, extracellular matrix protein |
10417 |
Q9BUD6 |
chr4: 1,166,932-1,208,962 |
EMILIN2 |
elastin microfibril interfacer 2 |
84034 |
Q9BXX0 |
chr18: 2,847,030-2,915,993 |
CRISPLD2 |
cysteine-rich secretory protein LCCL domain containing 2 |
83716 |
Q9H0B8 |
chr16: 84,819,984-84,920,768 |
WNT5B |
wingless-type MMTV integration site family member 5B |
81029 |
Q9H1J7 |
chr12: 1,529,891-1,647,243 |
SPON1 |
spondin 1, extracellular matrix protein |
10418 |
Q9HCB6 |
chr11: 13,962,689-14,267,884 |
CD248 |
CD248 molecule, endosialin |
57124 |
Q9HCU0 |
chr11: 66,314,487-66,317,044 |
MMP25 |
matrix metallopeptidase 25 |
64386 |
Q9NPA2 |
chr16: 3,046,681-3,060,726 |
CRTAC1 |
cartilage acidic protein 1 |
55118 |
Q9NQ79 |
chr10: 97,865,000-98,030,828 |
MMP26 |
matrix metallopeptidase 26 |
56547 |
Q9NRE1 |
chr11: 4,704,927-4,992,429 |
FLRT3 |
fibronectin leucine rich transmembrane protein 3 |
23767 |
Q9NZU0 |
chr20: 14,322,988-14,337,616 |
FLRT1 |
fibronectin leucine rich transmembrane protein 1 |
23769 |
Q9NZU1 |
chr11: 64,103,188-64,119,173 |
DSPP |
dentin sialophosphoprotein |
1834 |
Q9NZW4 |
chr4: 87,608,529-87,616,910 |
ADAMTS9 |
ADAM metallopeptidase with thrombospondin type 1 motif 9 |
56999 |
Q9P2N4 |
chr3: 64,515,654-64,688,000 |
ADAMTS7 |
ADAM metallopeptidase with thrombospondin type 1 motif 7 |
11173 |
Q9UKP4 |
chr15: 78,759,203-78,811,431 |
ADAMTS6 |
ADAM metallopeptidase with thrombospondin type 1 motif 6 |
11174 |
Q9UKP5 |
chr5: 65,148,736-65,481,920 |
ADAMTS5 |
ADAM metallopeptidase with thrombospondin type 1 motif 5 |
11096 |
Q9UNA0 |
chr21: 26,917,912-26,966,513 |
ADAMTS8 |
ADAM metallopeptidase with thrombospondin type 1 motif 8 |
11095 |
Q9UP79 |
chr11: 130,404,925-130,428,993 |
HPSE |
heparanase |
10855 |
Q9Y251 |
chr4: 83,292,461-83,335,153 |
MMP24 |
matrix metallopeptidase 24 |
10893 |
Q9Y5R2 |
chr20: 35,226,654-35,277,000 |
GPC6 |
glypican 6 |
10082 |
Q9Y625 |
chr13: 93,226,842-94,407,401 |
WNT6 |
wingless-type MMTV integration site family member 6 |
7475 |
Q9Y6F9 |
chr2: 218,859,821-218,874,233 |
LAMC3 |
laminin subunit gamma 3 |
10319 |
Q9Y6N6 |
chr9: 131,009,082-131,094,473 |