| GO ID | GO:0004867 |
| Ontology | MF |
| GO Term | serine-type endopeptidase inhibitor activity |
| Definition | Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. |
| Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
|---|---|---|---|---|
A2M | alpha-2-macroglobulin |
2 | P01023 | chr12: 9,067,664-9,116,229 |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
183 | P01019 | chr1: 230,702,523-230,714,297 |
AMBP | alpha-1-microglobulin/bikunin precursor |
259 | P02760 | chr9: 114,060,127-114,078,472 |
ANOS1 | anosmin 1 |
3730 | P23352 | chrX: 8,528,874-8,732,186 |
APLP2 | amyloid beta (A4) precursor-like protein 2 |
334 | Q06481 | chr11: 130,069,837-130,144,811 |
APP | amyloid beta (A4) precursor protein |
351 | P05067 | chr21: 25,880,550-26,171,128 |
COL6A3 | collagen, type VI, alpha 3 |
1293 | P12111 | chr2: 237,324,003-237,414,375 |
CPAMD8 | C3 and PZP-like, alpha-2-macroglobulin domain containing 8 |
27151 | Q8IZJ3 | chr19: 16,892,947-17,026,815 |
CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
51232 | Q9NZV1 | chr2: 36,355,926-36,551,135 |
FURIN | furin (paired basic amino acid cleaving enzyme) |
5045 | P09958 | chr15: 90,868,592-90,883,458 |
ITIH5 | inter-alpha-trypsin inhibitor heavy chain family member 5 |
80760 | Q86UX2 | chr10: 7,559,270-7,666,998 |
PAPLN | papilin, proteoglycan-like sulfated glycoprotein |
89932 | O95428 | chr14: 73,237,497-73,274,640 |
PEBP1 | phosphatidylethanolamine binding protein 1 |
5037 | P30086 | chr12: 118,135,858-118,145,584 |
RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
8434 | O95980 | chr9: 36,036,433-36,124,451 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
5265 | P01009 | chr14: 94,376,747-94,390,693 |
SERPINA12 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 |
145264 | Q8IW75 | chr14: 94,487,274-94,517,844 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
12 | P01011 | chr14: 94,612,377-94,624,055 |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
5104 | P05154 | chr14: 94,561,442-94,593,120 |
SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
1992 | P30740 | chr6: 2,832,332-2,842,006 |
SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
5275 | Q9UIV8 | chr18: 63,586,989-63,604,639 |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
6317 | P29508 | chr18: 63,655,197-63,661,963 |
SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
6318 | P48594 | chr18: 63,637,259-63,644,298 |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
5268 | P36952 | chr18: 63,476,761-63,505,085 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
5272 | P50453 | chr6: 2,887,266-2,903,280 |
SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 |
462 | P01008 | chr1: 173,903,804-173,917,378 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
5054 | P05121 | chr7: 101,127,089-101,139,266 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
5270 | P07093 | chr2: 223,975,112-224,039,319 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
5176 | P36955 | chr17: 1,761,959-1,777,574 |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
710 | P05155 | chr11: 57,597,387-57,614,853 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
871 | P50454 | chr11: 75,562,056-75,572,783 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
5274 | Q99574 | chr3: 167,735,243-167,825,568 |
SLPI | secretory leukocyte peptidase inhibitor |
6590 | P03973 | chr20: 45,252,239-45,254,564 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
6690 | P00995 | chr5: 147,824,568-147,831,786 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
10653 | O43291 | chr19: 38,244,035-38,292,614 |
TFPI | tissue factor pathway inhibitor |
7035 | P10646 | chr2: 187,464,230-187,565,760 |
TFPI2 | tissue factor pathway inhibitor 2 |
7980 | P48307 | chr7: 93,885,397-93,890,991 |
WFDC1 | WAP four-disulfide core domain 1 |
58189 | Q9HC57 | chr16: 84,294,646-84,329,851 |
WFDC2 | WAP four-disulfide core domain 2 |
10406 | Q14508 | chr20: 45,469,706-45,481,532 |
WFDC3 | WAP four-disulfide core domain 3 |
140686 | Q8IUB2 | chr20: 45,747,944-45,791,932 |