Gene Ontology Description

GO ID GO:0004867
Ontology MF
GO Term serine-type endopeptidase inhibitor activity
Definition Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

SPINT2

serine peptidase inhibitor, Kunitz type, 2

10653

O43291

chr19: 38,244,035-38,292,614

PAPLN

papilin, proteoglycan-like sulfated glycoprotein

89932

O95428

chr14: 73,237,497-73,274,640

RECK

reversion-inducing-cysteine-rich protein with kazal motifs

8434

O95980

chr9: 36,036,433-36,124,451

SPINK1

serine peptidase inhibitor, Kazal type 1

6690

P00995

chr5: 147,824,568-147,831,786

SERPINC1

serpin peptidase inhibitor, clade C (antithrombin), member 1

462

P01008

chr1: 173,903,804-173,917,378

SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

5265

P01009

chr14: 94,376,747-94,390,693

SERPINA3

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

12

P01011

chr14: 94,612,377-94,624,055

AGT

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

183

P01019

chr1: 230,702,523-230,714,297

A2M

alpha-2-macroglobulin

2

P01023

chr12: 9,067,664-9,116,229

AMBP

alpha-1-microglobulin/bikunin precursor

259

P02760

chr9: 114,060,127-114,078,472

SLPI

secretory leukocyte peptidase inhibitor

6590

P03973

chr20: 45,252,239-45,254,564

APP

amyloid beta (A4) precursor protein

351

P05067

chr21: 25,880,550-26,171,128

SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

5054

P05121

chr7: 101,127,089-101,139,266

SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

5104

P05154

chr14: 94,561,442-94,593,120

SERPING1

serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

710

P05155

chr11: 57,597,387-57,614,853

SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

5270

P07093

chr2: 223,975,112-224,039,319

FURIN

furin (paired basic amino acid cleaving enzyme)

5045

P09958

chr15: 90,868,592-90,883,458

TFPI

tissue factor pathway inhibitor

7035

P10646

chr2: 187,464,230-187,565,760

COL6A3

collagen, type VI, alpha 3

1293

P12111

chr2: 237,324,003-237,414,375

ANOS1

anosmin 1

3730

P23352

chrX: 8,528,874-8,732,186

SERPINB3

serpin peptidase inhibitor, clade B (ovalbumin), member 3

6317

P29508

chr18: 63,655,197-63,661,963

PEBP1

phosphatidylethanolamine binding protein 1

5037

P30086

chr12: 118,135,858-118,145,584

SERPINB1

serpin peptidase inhibitor, clade B (ovalbumin), member 1

1992

P30740

chr6: 2,832,332-2,842,006

SERPINB5

serpin peptidase inhibitor, clade B (ovalbumin), member 5

5268

P36952

chr18: 63,476,761-63,505,085

SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

5176

P36955

chr17: 1,761,959-1,777,574

TFPI2

tissue factor pathway inhibitor 2

7980

P48307

chr7: 93,885,397-93,890,991

SERPINB4

serpin peptidase inhibitor, clade B (ovalbumin), member 4

6318

P48594

chr18: 63,637,259-63,644,298

SERPINB9

serpin peptidase inhibitor, clade B (ovalbumin), member 9

5272

P50453

chr6: 2,887,266-2,903,280

SERPINH1

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

871

P50454

chr11: 75,562,056-75,572,783

APLP2

amyloid beta (A4) precursor-like protein 2

334

Q06481

chr11: 130,069,837-130,144,811

WFDC2

WAP four-disulfide core domain 2

10406

Q14508

chr20: 45,469,706-45,481,532

ITIH5

inter-alpha-trypsin inhibitor heavy chain family member 5

80760

Q86UX2

chr10: 7,559,270-7,666,998

WFDC3

WAP four-disulfide core domain 3

140686

Q8IUB2

chr20: 45,747,944-45,791,932

SERPINA12

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12

145264

Q8IW75

chr14: 94,487,274-94,517,844

CPAMD8

C3 and PZP-like, alpha-2-macroglobulin domain containing 8

27151

Q8IZJ3

chr19: 16,892,947-17,026,815

SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

5274

Q99574

chr3: 167,735,243-167,825,568

WFDC1

WAP four-disulfide core domain 1

58189

Q9HC57

chr16: 84,294,646-84,329,851

CRIM1

cysteine rich transmembrane BMP regulator 1 (chordin-like)

51232

Q9NZV1

chr2: 36,355,926-36,551,135

SERPINB13

serpin peptidase inhibitor, clade B (ovalbumin), member 13

5275

Q9UIV8

chr18: 63,586,989-63,604,639