Gene Ontology Description

GO ID GO:0002576
Ontology BP
GO Term platelet degranulation
Definition The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

ISLR

immunoglobulin superfamily containing leucine-rich repeat

3671

O14498

chr15: 74,173,671-74,176,872

ABCC4

ATP binding cassette subfamily C member 4

10257

O15439

chr13: 95,019,829-95,301,446

ACTN4

actinin, alpha 4

81

O43707

chr19: 38,647,649-38,731,583

WDR1

WD repeat domain 1

9948

O75083

chr4: 10,074,339-10,116,949

PHACTR2

phosphatase and actin regulator 2

9749

O75167

chr6: 143,536,845-143,831,185

F8

coagulation factor VIII, procoagulant component

2157

P00451

chrX: 154,835,788-155,026,940

F13A1

coagulation factor XIII, A1 polypeptide

2162

P00488

chr6: 6,144,085-6,321,013

PLG

plasminogen

5340

P00747

chr6: 160,702,238-160,753,315

SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

5265

P01009

chr14: 94,376,747-94,390,693

SERPINA3

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

12

P01011

chr14: 94,612,377-94,624,055

A2M

alpha-2-macroglobulin

2

P01023

chr12: 9,067,664-9,116,229

TIMP1

TIMP metallopeptidase inhibitor 1

7076

P01033

chrX: 47,582,313-47,586,789

KNG1

kininogen 1

3827

P01042

chr3: 186,717,276-186,743,954

PDGFB

platelet-derived growth factor beta polypeptide

5155

P01127

chr22: 39,223,359-39,244,751

TGFB1

transforming growth factor beta 1

7040

P01137

chr19: 41,301,587-41,353,911

IGF2

insulin like growth factor 2

3481

P01344

chr11: 2,129,112-2,141,238

APOA1

apolipoprotein A-I

335

P02647

chr11: 116,835,751-116,837,950

FGA

fibrinogen alpha chain

2243

P02671

chr4: 154,583,126-154,590,766

FGB

fibrinogen beta chain

2244

P02675

chr4: 154,562,956-154,571,086

FGG

fibrinogen gamma chain

2266

P02679

chr4: 154,604,134-154,612,967

APOH

apolipoprotein H

350

P02749

chr17: 66,212,033-66,256,525

FN1

fibronectin 1

2335

P02751

chr2: 215,360,440-215,436,172

ORM1

orosomucoid 1

5004

P02763

chr9: 114,323,056-114,326,475

AHSG

alpha-2-HS-glycoprotein

197

P02765

chr3: 186,612,923-186,621,318

ALB

albumin

213

P02768

chr4: 73,397,114-73,421,412

PPBP

pro-platelet basic protein

5473

P02775

chr4: 73,987,038-73,988,197

PF4

platelet factor 4

5196

P02776

chr4: 73,981,077-73,982,124

TF

transferrin

7018

P02787

chr3: 133,745,956-133,779,006

ALDOA

aldolase, fructose-bisphosphate A

226

P04075

chr16: 30,053,090-30,070,457

PDGFA

platelet-derived growth factor alpha polypeptide

5154

P04085

chr7: 497,258-520,296

A1BG

alpha-1-B glycoprotein

1

P04217

chr19: 58,345,178-58,353,499

VWF

von Willebrand factor

7450

P04275

chr12: 5,948,874-6,124,770

IGF1

insulin like growth factor 1

3479

P05019

chr12: 102,395,867-102,480,645

APP

amyloid beta (A4) precursor protein

351

P05067

chr21: 25,880,550-26,171,128

ITGB3

integrin subunit beta 3

3690

P05106

chr17: 47,253,846-47,311,816

SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

5054

P05121

chr7: 101,127,089-101,139,266

SERPING1

serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

710

P05155

chr11: 57,597,387-57,614,853

CLEC3B

C-type lectin domain family 3 member B

7123

P05452

chr3: 45,001,548-45,036,071

PSAP

prosaposin

5660

P07602

chr10: 71,816,298-71,851,375

LYN

LYN proto-oncogene, Src family tyrosine kinase

4067

P07948

chr8: 55,879,813-56,014,168

THBS1

thrombospondin 1

7057

P07996

chr15: 39,581,079-39,599,466

SPARC

secreted protein, acidic, cysteine-rich (osteonectin)

6678

P09486

chr5: 151,661,096-151,687,165

SRGN

serglycin

5552

P10124

chr10: 69,088,106-69,104,811

CLU

clusterin

1191

P10909

chr8: 27,596,917-27,615,031

F5

coagulation factor V (proaccelerin, labile factor)

2153

P12259

chr1: 169,514,166-169,586,588

ACTN1

actinin, alpha 1

87

P12814

chr14: 68,874,143-68,979,440

LAMP2

lysosomal-associated membrane protein 2

3920

P13473

chrX: 120,427,827-120,469,365

HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

3082

P14210

chr7: 81,699,006-81,770,438

VEGFA

vascular endothelial growth factor A

7422

P15692

chr6: 43,770,184-43,786,487

PECAM1

platelet/endothelial cell adhesion molecule 1

5175

P16284

chr17: 64,319,415-64,413,776

CD36

CD36 molecule (thrombospondin receptor)

948

P16671

chr7: 80,369,575-80,679,277

ORM2

orosomucoid 2

5005

P19652

chr9: 114,329,869-114,333,252

FLNA

filamin A

2316

P21333

chrX: 154,348,524-154,374,638

CD9

CD9 molecule

928

P21926

chr12: 6,199,715-6,238,271

ACTN2

actinin, alpha 2

88

P35609

chr1: 236,686,454-236,764,631

TIMP3

TIMP metallopeptidase inhibitor 3

7078

P35625

chr22: 32,801,701-32,863,043

VEGFB

vascular endothelial growth factor B

7423

P49765

chr11: 64,234,538-64,238,793

VEGFC

vascular endothelial growth factor C

7424

P49767

chr4: 176,683,538-176,792,727

SEPP1

selenoprotein P, plasma, 1

6414

P49908

chr5: 42,799,880-42,887,392

STXBP1

syntaxin binding protein 1

6812

P61764

chr9: 127,579,370-127,696,027

TGFB2

transforming growth factor beta 2

7042

P61812

chr1: 218,346,235-218,444,619

CALM2

calmodulin 2

805

P62158

chr2: 47,160,082-47,176,601

TMSB4X

thymosin beta 4, X-linked

7114

P62328

chrX: 12,975,108-12,977,227

TUBA4A

tubulin alpha 4a

7277

P68366

chr2: 219,249,711-219,278,170

APLP2

amyloid beta (A4) precursor-like protein 2

334

Q06481

chr11: 130,069,837-130,144,811

SPP2

secreted phosphoprotein 2

6694

Q13103

chr2: 234,050,679-234,077,134

MMRN1

multimerin 1

22915

Q13201

chr4: 89,879,532-89,954,629

GAS6

growth arrest specific 6

2621

Q14393

chr13: 113,820,549-113,864,067

HABP4

hyaluronan binding protein 4

22927

Q5JVS0

chr9: 96,450,201-96,491,336

TTN

titin

7273

Q8WZ42

chr2: 178,525,989-178,830,802

FAM3C

family with sequence similarity 3 member C

10447

Q92520

chr7: 121,348,851-121,396,364

RARRES2

retinoic acid receptor responder (tazarotene induced) 2

5919

Q99969

chr7: 150,338,317-150,341,674

TLN1

talin 1

7094

Q9Y490

chr9: 35,696,948-35,732,395