| Interpro ID |
Description |
Proteins |
|
IPR020578
|
Aminotransferase class-V, pyridoxal-phosphate binding site
|
AGXT,
PSAT1
|
|
IPR020583
|
Inositol monophosphatase, metal-binding site
|
IMPA1,
INPP1
|
|
IPR020587
|
DNA recombination and repair protein RecA, monomer-monomer interface
|
RAD51
|
|
IPR020588
|
DNA recombination and repair protein RecA-like, ATP-binding domain
|
RAD51C,
RAD51D,
RAD51
|
|
IPR020590
|
Guanylate kinase, conserved site
|
CASK,
DLG4,
MPP1,
DLG1,
GUK1,
MAGI2,
MPP5,
MAGI1,
MPP6
|
|
IPR020593
|
Gamma-glutamyl phosphate reductase GPR, conserved site
|
ALDH18A1
|
|
IPR020596
|
Ribosomal RNA adenine methylase transferase, conserved site
|
DIMT1
|
|
IPR020598
|
Ribosomal RNA adenine methylase transferase, N-terminal
|
DIMT1
|
|
IPR020604
|
CTF transcription factor/nuclear factor 1, DNA-binding domain
|
NFIB,
NFIC
|
|
IPR020606
|
Ribosomal protein S7, conserved site
|
RPS5
|
|
IPR020608
|
RNA polymerase, subunit H/Rpb5, conserved site
|
POLR2E
|
|
IPR020609
|
Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit
|
POLR2E
|
|
IPR020610
|
Thiolase, active site
|
HADHB,
ACAT2
|
|
IPR020611
|
Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site
|
PAM
|
|
IPR020612
|
Methylthiotransferase, conserved site
|
CDKAL1
|
|
IPR020613
|
Thiolase, conserved site
|
SCP2,
HADHB,
ACAT2
|
|
IPR020615
|
Thiolase, acyl-enzyme intermediate active site
|
SCP2,
HADHB
|
|
IPR020616
|
Thiolase, N-terminal
|
SCP2,
HADHB,
ACAT2
|
|
IPR020617
|
Thiolase, C-terminal
|
SCP2,
HADHB,
ACAT2
|
|
IPR020628
|
Formate-tetrahydrofolate ligase, FTHFS, conserved site
|
MTHFD1,
MTHFD1L
|
|
IPR020630
|
Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
|
MTHFD1,
MTHFD2,
MTHFD1L,
MTHFD2L
|
|
IPR020631
|
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
|
MTHFD1,
MTHFD2,
MTHFD1L,
MTHFD2L
|
|
IPR020633
|
Thymidine kinase, conserved site
|
TK1
|
|
IPR020635
|
Tyrosine-protein kinase, catalytic domain
|
MUSK,
JAK2,
EGFR,
ERBB2,
NTRK1,
INSR,
FYN,
CSF1R,
LYN,
IGF1R,
MET,
PDGFRB,
FGR,
KIT,
FGFR1,
PDGFRA,
FGFR2,
JAK1,
EPHA3,
EPHB2,
LTK,
TIE1,
FLT4,
CSK,
ABL2,
SYK,
JAK3,
EPHA5,
EPHB4,
EPHB1,
EPHA4,
TEK,
PTK2,
TYRO3,
TNK2,
DDR1,
MERTK,
ERBB4,
NTRK2,
EPHA6
|
|
IPR020636
|
Calcium/calmodulin-dependent/calcium-dependent protein kinase
|
DCLK1,
DAPK3,
PSKH1,
CAMK2D,
CAMK1,
STK11,
PNCK,
CAMK1D
|
|
IPR020676
|
Death-associated protein kinase 1
|
DAPK1
|
|
IPR020683
|
Ankyrin repeat-containing domain
|
ASB14,
ANKRD36,
KRIT1,
PPP1R12A,
ANKRD28,
ASAP2,
PPP1R12B,
PSMD10,
GLS,
TNKS,
NFKB1,
BCL3,
CDKN2B,
CDKN2C,
NOTCH1,
TRPC1,
DAPK1,
MTPN,
ANK2,
NOTCH2,
RNASEL,
AKAP13,
ANK3,
ILK,
TRPC3,
DGKZ,
TP53BP2,
GIT2,
KANK1,
ACAP2,
ANKRD1,
ANKRD55,
ANKRD20A4,
SOWAHC,
ANKRD39,
ANKRD20A8P,
BCORL1,
ANKRD20A2,
KANK4,
ANKRD20A1,
ANKRD45,
ANKRD20A3,
ANKRD22,
KANK2,
ANKRD40,
POTEE,
ANKRD12,
ANKRD11,
ANKRD46,
ANKLE2,
MIB1,
ZDHHC17,
ANKRD18A,
TEX14,
HACE1,
ANKRD13A,
ARHGEF28,
ANKRD36B,
CLIP4,
ANKRD29,
ABTB2,
ANKRD42,
TRPV1,
ANKK1,
GABPB2,
PPP1R13L,
ANKS1A,
MIB2,
TONSL,
FEM1C,
EHMT2,
ASB16,
ANKRD27,
AGAP4,
MPHOSPH8,
BARD1,
SLF1,
FEM1A,
OSBPL1A,
NFKBIZ,
UACA,
TRPV6,
TNKS2,
YTHDC2,
ASB8,
TRPV4,
TANC2,
ANKRD10,
ANKFY1,
NFKBIL1,
FEM1B,
KIDINS220,
ASAP1,
ANKRD50,
AGAP1,
TRPC6,
INVS,
GIT1,
ASB3,
TRPV2,
SNCAIP,
CAMTA1
|
|
IPR020684
|
Rho-associated protein kinase 1/2
|
ROCK2
|
|
IPR020693
|
Tyrosine-protein kinase, non-receptor Jak2
|
JAK2
|
|
IPR020717
|
Apoptosis regulator, Bcl-2, BH1 motif, conserved site
|
BCL2,
BAX,
MCL1,
BCL2L2
|
|
IPR020719
|
RNA 3'-terminal phosphate cyclase-like, conserved site
|
RTCA,
RCL1
|
|
IPR020726
|
Apoptosis regulator, Bcl-2, BH2 motif, conserved site
|
BCL2,
BAX,
MCL1,
BCL2L2
|
|
IPR020728
|
Apoptosis regulator, Bcl-2, BH3 motif, conserved site
|
BCL2,
BID,
BAX,
MCL1
|
|
IPR020731
|
Apoptosis regulator, Bcl-2, BH4 motif, conserved site
|
BCL2,
BCL2L2
|
|
IPR020751
|
Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2
|
EARS2
|
|
IPR020775
|
Tyrosine-protein kinase, non-receptor Jak3
|
JAK3
|
|
IPR020776
|
Tyrosine-protein kinase, non-receptor Jak1
|
JAK1
|
|
IPR020777
|
Tyrosine-protein kinase, neurotrophic receptor
|
NTRK1,
NTRK2
|
|
IPR020781
|
ATPase, OSCP/delta subunit, conserved site
|
ATP5O
|
|
IPR020783
|
Ribosomal protein L11, C-terminal
|
RPL12
|
|
IPR020784
|
Ribosomal protein L11, N-terminal
|
RPL12
|
|
IPR020785
|
Ribosomal protein L11, conserved site
|
RPL12
|
|
IPR020789
|
RNA polymerases, subunit N, zinc binding site
|
POLR2L
|
|
IPR020795
|
Origin recognition complex, subunit 3
|
ORC3
|
|
IPR020796
|
Origin recognition complex, subunit 5
|
ORC5
|
|
IPR020801
|
Polyketide synthase, acyl transferase domain
|
FASN
|
|
IPR020806
|
Polyketide synthase, phosphopantetheine-binding domain
|
FASN
|
|
IPR020807
|
Polyketide synthase, dehydratase domain
|
FASN
|
|
IPR020809
|
Enolase, conserved site
|
ENO1,
ENO2,
ENO3
|
|
IPR020810
|
Enolase, C-terminal TIM barrel domain
|
ENO1,
ENO2,
ENO3
|
|
IPR020811
|
Enolase, N-terminal
|
ENO1,
ENO2,
ENO3
|
|
IPR020818
|
GroES chaperonin family
|
HSPE1
|
|
IPR020821
|
Extracellular Endonuclease, subunit A
|
ENPP3,
ENPP1,
ENPP2,
EXOG
|
|
IPR020826
|
Transketolase binding site
|
TKT
|
|
IPR020828
|
Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
|
GAPDH
|
|
IPR020829
|
Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
|
GAPDH
|
|
IPR020830
|
Glyceraldehyde 3-phosphate dehydrogenase, active site
|
GAPDH
|
|
IPR020831
|
Glyceraldehyde/Erythrose phosphate dehydrogenase family
|
GAPDH
|
|
IPR020833
|
Lipoxygenase, iron binding site
|
ALOX5,
ALOX15
|
|
IPR020834
|
Lipoxygenase, conserved site
|
ALOX5,
ALOX15
|
|
IPR020837
|
Fibrinogen, conserved site
|
ANGPT2,
ANGPTL1,
FGA,
FGB,
FGG,
TNXB,
FGL2,
ANGPT1,
FCN2
|
|
IPR020838
|
DBINO domain
|
SMARCA5,
SMARCA1
|
|
IPR020841
|
Polyketide synthase, beta-ketoacyl synthase domain
|
FASN
|
|
IPR020843
|
Polyketide synthase, enoylreductase domain
|
CRYZL1,
ADH1B,
FASN,
SORD,
CRYZ,
PTGR1,
ZADH2,
RTN4IP1,
MECR
|
|
IPR020845
|
AMP-binding, conserved site
|
SLC27A2,
ACSL4,
ACSL1,
AASDH,
ACSM3,
SLC27A4,
SLC27A1,
AACS,
ACSS3,
ACSS2,
ACSS1,
ACSL6,
SLC27A6
|
|
IPR020846
|
Major facilitator superfamily domain
|
SLC22A23,
SLC33A1,
SLC22A1,
SLC16A6,
SLC16A3,
SLC37A4,
SLC16A7,
SLC19A2,
SLC22A3,
SLC22A5,
SLCO2B1,
SLC2A10,
SLC2A1,
SLC2A3,
SLC2A4,
SLC2A5,
SLC19A1,
SLC18A2,
CLN3,
SLC15A2,
OCLN,
MFSD14B,
MFSD4B,
MFSD5,
SLC18B1,
SLCO4C1,
SLC16A12,
MFSD6,
SV2A,
SV2B,
SLC16A14,
SLC16A9,
SLCO6A1,
SLC15A4,
MFSD2A,
SLC43A3,
MFSD8,
SLC2A14,
SLC16A10,
SLCO2A1,
SLC22A18,
MFSD14A,
SLC46A1,
SLC29A1,
SLC46A2,
MFSD1,
SLC40A1,
SLC2A6,
SLCO3A1,
SLC45A2,
FLVCR2,
SLC45A1
|
|
IPR020849
|
Small GTPase superfamily, Ras type
|
DIRAS3,
NRAS,
KRAS,
RAP2A,
RRAS,
RALA,
RALB,
GEM,
RRAD,
RAP2B,
RRAS2,
RAP1A,
RHEB,
RHEBL1,
RIT1,
RERG,
RASD2,
RASL10B,
RASL11B,
NKIRAS1,
RASD1
|
|
IPR020850
|
GTPase effector domain
|
DNM1P46
|
|
IPR020855
|
Ureohydrolase, manganese-binding site
|
AGMAT
|
|
IPR020857
|
Serum albumin, conserved site
|
ALB,
GC
|
|
IPR020858
|
Serum albumin-like
|
ALB,
GC
|
|
IPR020859
|
Roc domain
|
DAPK1,
MFHAS1
|
|
IPR020861
|
Triosephosphate isomerase, active site
|
TPI1
|
|
IPR020863
|
Membrane attack complex component/perforin domain, conserved site
|
C7,
C6
|
|
IPR020864
|
Membrane attack complex component/perforin (MACPF) domain
|
BRINP1,
C7,
C6
|
|
IPR020867
|
Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site
|
MTHFD1,
MTHFD2,
MTHFD2L
|
|
IPR020877
|
Interleukin-1 conserved site
|
IL1A,
IL1B,
IL1RN
|
|
IPR020892
|
Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
|
PPIH,
PPIB,
PPIF,
NKTR,
PPIC,
RANBP2,
PPIA,
PPID,
PPIL2,
PPIG,
CWC27,
PPIE
|
|
IPR020893
|
Cytochrome c oxidase, subunit Vb, zinc binding site
|
COX5B
|
|
IPR020894
|
Cadherin conserved site
|
PCDH17,
CDH2,
CDH5,
CDH6,
CDH11,
CDH12,
CDH13,
CDH15,
DSC2,
PCDH1,
CDH17,
DSG2,
FAT1,
PCDH19,
FAT3,
CDHR2,
PCDH11Y,
PCDHAC1,
PCDH9,
PCDH18,
CELSR3,
PCDH10,
CDH22,
PCDHGC3,
PCDHA7,
PCDHA6,
PCDHA4,
PCDHA12,
PCDHB9,
PCDHB3,
PCDHB14,
PCDHA9,
PCDHA8,
PCDHA5,
PCDHA3,
PCDHA2,
PCDHA13,
PCDHA11,
PCDHA10,
PCDHA1,
PCDHAC2
|
|
IPR020895
|
Frataxin conserved site
|
FXN
|
|
IPR020897
|
Synapsin, pre-ATP-grasp domain
|
SYN1,
SYN2
|
|
IPR020898
|
Synapsin, ATP-binding domain
|
SYN1,
SYN2
|
|
IPR020901
|
Proteinase inhibitor I2, Kunitz, conserved site
|
SPINT2,
PAPLN,
AMBP,
APP,
TFPI,
COL6A3,
TFPI2,
APLP2
|
|
IPR020902
|
Actin/actin-like conserved site
|
ACTR1B,
ACTB,
ACTR3,
ACTR2,
ACTA2,
ACTG1,
ACTG2,
ACTC1,
POTEE
|
|
IPR020903
|
Epithelial sodium channel, conserved site
|
SCNN1A,
SCNN1G,
ASIC2,
ASIC3
|
|
IPR020904
|
Short-chain dehydrogenase/reductase, conserved site
|
HSD17B6,
QDPR,
HSD17B1,
HPGD,
CBR1,
HSD11B1,
HSD17B2,
HSD17B4,
HSD11B2,
HSD17B12,
HSDL2,
DCXR,
RDH10,
RDH13,
HSD17B10,
DHRS4,
BDH2,
DHRS7
|
|
IPR020925
|
Ribosomal protein L15e, conserved site
|
RPL15
|
|
IPR020929
|
Ribosomal protein L5, conserved site
|
RPL11
|
|
IPR020940
|
Thymidylate synthase, active site
|
TYMS
|
|
IPR020941
|
Suppressor of fused-like domain
|
SUFU
|
|
IPR020946
|
Flavin monooxygenase-like
|
FMO4,
FMO2
|
|
IPR020950
|
Protein male abnormal 21-like 1/2
|
MAB21L1
|
|
IPR020987
|
Centromere protein Cenp-M
|
CENPM
|
|
IPR020989
|
Histone-arginine methyltransferase CARM1, N-terminal
|
CARM1
|
|
IPR020993
|
Centromere protein Cenp-K
|
CENPK
|
|
IPR020997
|
Capicua transcriptional repressor modulator, Ataxin-1
|
ATXN1
|
|
IPR021019
|
Mediator complex, subunit Med30, metazoa
|
MED30
|
|
IPR021025
|
Fanconi Anaemia group E protein, C-terminal
|
FANCE
|
|
IPR021040
|
LRRC8, pannexin-like TM region
|
LRRC8B,
LRRC8A,
LRRC8C
|