Disease Description

UMLS CUI C0024141
UMLS Term Lupus Erythematosus, Systemic
MeSH ID D008180
MeSH Term Lupus Erythematosus, Systemic
Disease Classes

Skin and Connective Tissue Diseases

Immune System Diseases

Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

SH2B3

SH2B adaptor protein 3

10019

Q9UQQ2

chr12: 111,405,948-111,451,623

CDKN1B

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

1027

P46527

chr12: 12,715,058-12,722,371

IKZF1

IKAROS family zinc finger 1

10320

Q13422

chr7: 50,304,124-50,405,101

CLU

clusterin

1191

P10909

chr8: 27,596,917-27,615,031

SLC15A4

solute carrier family 15 (oligopeptide transporter), member 4

121260

Q8N697

chr12: 128,793,191-128,823,983

CREBL2

cAMP responsive element binding protein-like 2

1389

O60519

chr12: 12,611,827-12,645,108

CRP

C-reactive protein, pentraxin-related

1401

P02741

chr1: 159,712,289-159,714,589

CSK

c-src tyrosine kinase

1445

P41240

chr15: 74,782,057-74,803,198

ETS1

v-ets avian erythroblastosis virus E26 oncogene homolog 1

2113

P14921

chr11: 128,458,761-128,587,558

FCGR2A

Fc fragment of IgG, low affinity IIa, receptor (CD32)

2212

P12318

chr1: 161,505,430-161,524,013

FCGR2B

Fc fragment of IgG, low affinity IIb, receptor (CD32)

2213

P31994

chr1: 161,663,147-161,678,654

JAZF1

JAZF zinc finger 1

221895

Q86VZ6

chr7: 27,830,573-28,180,743

ANKS1A

ankyrin repeat and sterile alpha motif domain containing 1A

23294

Q92625

chr6: 34,889,265-35,091,413

TNPO3

transportin 3

23534

Q9Y5L0

chr7: 128,954,180-129,055,173

PTPN22

protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

26191

Q9Y2R2

chr1: 113,813,811-113,871,759

FAM98B

family with sequence similarity 98 member B

283742

Q52LJ0

chr15: 38,454,127-38,487,710

ANXA3

annexin A3

306

P12429

chr4: 78,551,519-78,610,451

HIP1

huntingtin interacting protein 1

3092

O00291

chr7: 75,533,300-75,738,962

HLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

3117

P01909

chr6: 32,628,179-32,647,062

HLA-DRB1

major histocompatibility complex, class II, DR beta 1

3123

P04229

chr6: 32,578,769-32,589,848

IL6

interleukin 6

3569

P05231

chr7: 22,725,884-22,732,002

IL10

interleukin 10

3586

P22301

chr1: 206,767,602-206,772,494

ITGAM

integrin subunit alpha M

3684

P11215

chr16: 31,259,990-31,332,892

ITGAX

integrin subunit alpha X

3687

P20702

chr16: 31,355,134-31,382,997

PXK

PX domain containing serine/threonine kinase

54899

Q7Z7A4

chr3: 58,332,880-58,426,126

PRL

prolactin

5617

P01236

chr6: 22,287,244-22,297,501

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

5743

P35354

chr1: 186,671,791-186,680,427

PHRF1

PHD and ring finger domains 1

57661

Q9P1Y6

chr11: 576,486-612,222

CFB

complement factor B

629

P00751

chr6: 31,945,650-31,952,084

TLR5

toll-like receptor 5

7100

O60602

chr1: 223,109,406-223,143,282

C1QA

complement component 1, q subcomponent, A chain

712

P02745

chr1: 22,636,506-22,639,608

TNFAIP3

TNF alpha induced protein 3

7128

P21580

chr6: 137,867,188-137,883,312

TNXB

tenascin XB

7148

P22105

chr6: 32,041,154-32,115,334

C4A

complement component 4A (Rodgers blood group)

720

P0C0L4

chr6: 31,982,024-32,002,681

TNFSF4

tumor necrosis factor superfamily member 4

7292

P23510

chr1: 173,183,734-173,207,313

DDA1

DET1 and DDB1 associated 1

79016

Q9BW61

chr19: 17,309,518-17,323,301

KIAA0319L

KIAA0319-like

79932

Q8IZA0

chr1: 35,433,490-35,557,950

ARID5B

AT-rich interaction domain 5B

84159

Q14865

chr10: 61,901,300-62,096,944