Disease Description

UMLS CUI C0011860
UMLS Term Diabetes Mellitus, Non-Insulin-Dependent
MeSH ID D003924
MeSH Term Diabetes Mellitus, Type 2
Disease Classes

Nutritional and Metabolic Diseases

Endocrine System Diseases

Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

MPHOSPH9

M-phase phosphoprotein 9

10198

Q99550

chr12: 123,152,320-123,244,014

AP3S2

adaptor related protein complex 3, sigma 2 subunit

10239

P59780

chr15: 89,830,599-89,894,638

MAEA

macrophage erythroblast attacher

10296

Q7L5Y9

chr4: 1,289,851-1,340,147

CDO1

cysteine dioxygenase type 1

1036

Q16878

chr5: 115,804,733-115,816,954

HMG20A

high mobility group 20A

10363

Q9NP66

chr15: 77,420,412-77,485,607

IGF2BP2

insulin like growth factor 2 mRNA binding protein 2

10644

Q9Y6M1

chr3: 185,643,739-185,825,056

PPARGC1A

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

10891

Q9UBK2

chr4: 23,755,041-23,904,089

KCNQ1OT1

KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)

10984

N/A

chr11: 2,608,328-2,699,994

FAF1

Fas (TNFRSF6) associated factor 1

11124

Q9UNN5

chr1: 50,437,028-50,960,263

CAPN10

calpain 10

11132

Q9HC96

chr2: 240,586,716-240,617,705

OSBPL1A

oxysterol binding protein like 1A

114876

Q9BXW6

chr18: 24,162,044-24,397,880

ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

116985

Q96P48

chr11: 72,685,069-72,793,599

CPT1A

carnitine palmitoyltransferase 1A (liver)

1374

P50416

chr11: 68,754,620-68,844,410

SLC30A8

solute carrier family 30 (zinc transporter), member 8

169026

Q8IWU4

chr8: 116,950,273-117,176,714

GLIS3

GLIS family zinc finger 3

169792

Q8NEA6

chr9: 3,824,127-4,348,392

ECE1

endothelin converting enzyme 1

1889

P42892

chr1: 21,217,247-21,345,504

EDN1

endothelin 1

1906

P05305

chr6: 12,290,363-12,297,194

EDNRA

endothelin receptor type A

1909

P25101

chr4: 147,480,917-147,544,954

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

AKT2

v-akt murine thymoma viral oncogene homolog 2

208

P31751

chr19: 40,230,317-40,285,536

JAZF1

JAZF zinc finger 1

221895

Q86VZ6

chr7: 27,830,573-28,180,743

GPSM1

G-protein signaling modulator 1

26086

Q86YR5

chr9: 136,327,476-136,359,605

GCG

glucagon

2641

P01275

chr2: 162,142,873-162,152,404

GNB3

guanine nucleotide binding protein (G protein), beta polypeptide 3

2784

P16520

chr12: 6,839,954-6,847,393

GPD2

glycerol-3-phosphate dehydrogenase 2

2820

P43304

chr2: 156,435,290-156,613,735

GRK5

G protein-coupled receptor kinase 5

2869

P34947

chr10: 119,207,589-119,459,742

GPX1

glutathione peroxidase 1

2876

P07203

chr3: 49,357,176-49,358,600

GRB14

growth factor receptor bound protein 14

2888

Q14449

chr2: 164,492,812-164,621,848

GSTM1

glutathione S-transferase mu 1

2944

P09488

chr1: 109,687,814-109,709,039

HBA1

hemoglobin subunit alpha 1

3039

P69905

chr16: 176,680-177,522

HHEX

hematopoietically expressed homeobox

3087

Q03014

chr10: 92,689,951-92,695,646

HK1

hexokinase 1

3098

P19367

chr10: 69,269,984-69,401,882

HMGA1

high mobility group AT-hook 1

3159

P17096

chr6: 34,236,873-34,246,231

HMOX1

heme oxygenase 1

3162

P09601

chr22: 35,380,361-35,394,214

HP

haptoglobin

3240

P00738

chr16: 72,054,592-72,061,055

IAPP

islet amyloid polypeptide

3375

P10997

chr12: 21,354,959-21,379,978

ICAM1

intercellular adhesion molecule 1

3383

P05362

chr19: 10,270,835-10,286,615

ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

3397

P41134

chr20: 31,605,283-31,606,515

FAS

Fas cell surface death receptor

355

P25445

chr10: 88,990,582-89,015,785

IL6

interleukin 6

3569

P05231

chr7: 22,725,884-22,732,002

INS

insulin

3630

P01308

chr11: 2,159,779-2,161,341

INSR

insulin receptor

3643

P06213

chr19: 7,112,255-7,294,034

IRS1

insulin receptor substrate 1

3667

P35568

chr2: 226,731,317-226,799,759

KCNJ11

potassium channel, inwardly rectifying subfamily J, member 11

3767

Q14654

chr11: 17,385,859-17,389,331

LEP

leptin

3952

P41159

chr7: 128,241,284-128,257,628

LEPR

leptin receptor

3953

P48357

chr1: 65,420,652-65,641,559

MTNR1B

melatonin receptor 1B

4544

P49286

chr11: 92,969,720-92,985,066

ATF3

activating transcription factor 3

467

P18847

chr1: 212,565,334-212,620,777

NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

4790

P19838

chr4: 102,501,329-102,617,302

NOS3

nitric oxide synthase 3

4846

P29474

chr7: 150,990,995-151,014,588

NOTCH2

notch 2

4853

Q04721

chr1: 119,911,553-120,069,626

ATP2A2

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

488

P16615

chr12: 110,280,756-110,351,093

PAM

peptidylglycine alpha-amidating monooxygenase

5066

P19021

chr5: 102,753,981-103,031,105

PAX4

paired box 4

5078

O43316

chr7: 127,610,292-127,618,114

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

5167

P22413

chr6: 131,808,016-131,895,155

POU5F1

POU class 5 homeobox 1

5460

Q01860

chr6: 31,164,337-31,180,731

PPARA

peroxisome proliferator-activated receptor alpha

5465

Q07869

chr22: 46,150,521-46,243,756

PPARG

peroxisome proliferator-activated receptor gamma

5468

P37231

chr3: 12,287,368-12,434,356

CDKAL1

CDK5 regulatory subunit associated protein 1-like 1

54901

Q5VV42

chr6: 20,534,457-21,232,404

PPP1R3A

protein phosphatase 1 regulatory subunit 3A

5506

Q16821

chr7: 113,876,777-114,075,920

ITLN1

intelectin 1 (galactofuranose binding)

55600

Q8WWA0

chr1: 160,876,539-160,885,170

PRKCB

protein kinase C, beta

5579

P05771

chr16: 23,836,001-24,220,611

PROX1

prospero homeobox 1

5629

Q92786

chr1: 213,983,181-214,041,502

RETN

resistin

56729

Q9HD89

chr19: 7,669,044-7,670,454

ADAMTS9

ADAM metallopeptidase with thrombospondin type 1 motif 9

56999

Q9P2N4

chr3: 64,515,654-64,688,000

ZMIZ1

zinc finger, MIZ-type containing 1

57178

Q9ULJ6

chr10: 79,069,035-79,316,528

PTPRD

protein tyrosine phosphatase, receptor type, D

5789

P23468

chr9: 8,314,246-10,612,723

RBMS1

RNA binding motif, single stranded interacting protein 1

5937

P29558

chr2: 160,272,151-160,493,794

BCL2

B-cell CLL/lymphoma 2

596

P10415

chr18: 63,123,346-63,320,128

RELA

v-rel avian reticuloendotheliosis viral oncogene homolog A

5970

Q04206

chr11: 65,653,596-65,663,094

RGS7

regulator of G-protein signaling 7

6000

P49802

chr1: 240,775,515-241,357,230

RNF6

ring finger protein (C3H2C3 type) 6

6049

Q9Y252

chr13: 26,132,115-26,222,493

ZFAND3

zinc finger, AN1-type domain 3

60685

Q9H8U3

chr6: 37,819,499-38,154,624

S100A6

S100 calcium binding protein A6

6277

P06703

chr1: 153,534,599-153,536,244

THADA

thyroid adenoma associated

63892

Q6YHU6

chr2: 43,230,836-43,596,046

SHBG

sex hormone-binding globulin

6462

P04278

chr17: 7,613,946-7,633,383

ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

6480

P15907

chr3: 186,930,485-187,078,553

SLC2A1

solute carrier family 2 (facilitated glucose transporter), member 1

6513

P11166

chr1: 42,925,375-42,959,173

SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

6517

P14672

chr17: 7,281,667-7,288,257

SNAP25

synaptosome associated protein 25kDa

6616

P60880

chr20: 10,218,830-10,307,418

SOD2

superoxide dismutase 2, mitochondrial

6648

P04179

chr6: 159,669,057-159,762,529

HNF1A

HNF1 homeobox A

6927

P20823

chr12: 120,978,543-121,002,512

TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

6934

Q9NQB0

chr10: 112,950,250-113,167,678

TGFB1

transforming growth factor beta 1

7040

P01137

chr19: 41,301,587-41,353,911

TIMP1

TIMP metallopeptidase inhibitor 1

7076

P01033

chrX: 47,582,313-47,586,789

TNF

tumor necrosis factor

7124

P01375

chr6: 31,575,567-31,578,336

TNFRSF1B

tumor necrosis factor receptor superfamily member 1B

7133

P20333

chr1: 12,167,003-12,209,228

C3

complement component 3

718

P01024

chr19: 6,677,704-6,730,562

UBE2E2

ubiquitin conjugating enzyme E2E 2

7325

Q96LR5

chr3: 23,203,020-23,591,793

UCP2

uncoupling protein 2 (mitochondrial, proton carrier)

7351

P55851

chr11: 73,974,667-73,983,307

VEGFA

vascular endothelial growth factor A

7422

P15692

chr6: 43,770,184-43,786,487

FTO

fat mass and obesity associated

79068

Q9C0B1

chr16: 53,701,692-54,158,512

CMIP

c-Maf inducing protein

80790

Q8IY22

chr16: 81,445,170-81,711,762

HMGA2

high mobility group AT-hook 2

8091

P52926

chr12: 65,824,131-65,966,295

CASP8

caspase 8

841

Q14790

chr2: 201,233,443-201,287,711

IRS2

insulin receptor substrate 2

8660

Q9Y4H2

chr13: 109,752,698-109,786,568

CBS

cystathionine-beta-synthase

875

P35520

chr21: 43,053,191-43,076,943

CCND2

cyclin D2

894

P30279

chr12: 4,273,772-4,305,350

KCNK17

potassium channel, two pore domain subfamily K, member 17

89822

Q96T54

chr6: 39,299,001-39,314,553

PRC1

protein regulator of cytokinesis 1

9055

O43663

chr15: 90,966,038-90,995,629

DNER

delta/notch like EGF repeat containing

92737

Q8NFT8

chr2: 229,357,629-229,714,558

ADIPOQ

adiponectin, C1Q and collagen domain containing

9370

Q15848

chr3: 186,842,690-186,858,463

TP53INP1

tumor protein p53 inducible nuclear protein 1

94241

Q96A56

chr8: 94,925,972-94,949,411

MAPK8IP1

mitogen-activated protein kinase 8 interacting protein 1

9479

Q9UQF2

chr11: 45,885,651-45,906,465

VPS26A

VPS26 retromer complex component A

9559

O75436

chr10: 69,123,512-69,172,861