Disease Description

UMLS CUI C0011853
UMLS Term Diabetes Mellitus, Experimental
MeSH ID D003921
MeSH Term Diabetes Mellitus, Experimental
Disease Classes

Nutritional and Metabolic Diseases

Endocrine System Diseases

Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

PPARGC1A

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

10891

Q9UBK2

chr4: 23,755,041-23,904,089

CHRM2

cholinergic receptor, muscarinic 2

1129

P08172

chr7: 136,868,669-137,020,255

CPT1A

carnitine palmitoyltransferase 1A (liver)

1374

P50416

chr11: 68,754,620-68,844,410

CPT1B

carnitine palmitoyltransferase 1B

1375

Q92523

chr22: 50,568,861-50,578,465

ADRA1A

adrenoceptor alpha 1A

148

P35348

chr8: 26,748,150-26,867,273

CYBB

cytochrome b-245, beta polypeptide

1536

P04839

chrX: 37,780,011-37,813,461

CYP1A1

cytochrome P450 family 1 subfamily A member 1

1543

P04798

chr15: 74,719,542-74,725,610

ADRB3

adrenoceptor beta 3

155

P13945

chr8: 37,962,991-37,966,965

ACE

angiotensin I converting enzyme

1636

P12821

chr17: 63,477,061-63,498,380

NQO1

NAD(P)H dehydrogenase, quinone 1

1728

P15559

chr16: 69,706,996-69,726,951

AGT

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

183

P01019

chr1: 230,702,523-230,714,297

EDN1

endothelin 1

1906

P05305

chr6: 12,290,363-12,297,194

ESRRA

estrogen-related receptor alpha

2101

P11474

chr11: 64,305,572-64,316,743

ACSL1

acyl-CoA synthetase long-chain family member 1

2180

P33121

chr4: 184,755,595-184,826,818

FOXO3

forkhead box O3

2309

O43524

chr6: 108,559,835-108,684,774

GPD2

glycerol-3-phosphate dehydrogenase 2

2820

P43304

chr2: 156,435,290-156,613,735

GPX1

glutathione peroxidase 1

2876

P07203

chr3: 49,357,176-49,358,600

GSR

glutathione reductase

2936

P00390

chr8: 30,678,061-30,727,926

HK1

hexokinase 1

3098

P19367

chr10: 69,269,984-69,401,882

HMOX1

heme oxygenase 1

3162

P09601

chr22: 35,380,361-35,394,214

HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

3290

P28845

chr1: 209,686,178-209,734,950

IAPP

islet amyloid polypeptide

3375

P10997

chr12: 21,354,959-21,379,978

ICAM1

intercellular adhesion molecule 1

3383

P05362

chr19: 10,270,835-10,286,615

ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

3397

P41134

chr20: 31,605,283-31,606,515

IGF1

insulin like growth factor 1

3479

P05019

chr12: 102,395,867-102,480,645

FAS

Fas cell surface death receptor

355

P25445

chr10: 88,990,582-89,015,785

IL1B

interleukin 1 beta

3553

P01584

chr2: 112,829,751-112,836,903

IL6

interleukin 6

3569

P05231

chr7: 22,725,884-22,732,002

INSR

insulin receptor

3643

P06213

chr19: 7,112,255-7,294,034

IRS1

insulin receptor substrate 1

3667

P35568

chr2: 226,731,317-226,799,759

KCNJ11

potassium channel, inwardly rectifying subfamily J, member 11

3767

Q14654

chr11: 17,385,859-17,389,331

LEPR

leptin receptor

3953

P48357

chr1: 65,420,652-65,641,559

STS

steroid sulfatase (microsomal), isozyme S

412

P08842

chrX: 7,219,456-7,354,810

MAP3K5

mitogen-activated protein kinase kinase kinase 5

4217

Q99683

chr6: 136,557,047-136,792,518

MFGE8

milk fat globule-EGF factor 8 protein

4240

Q08431

chr15: 88,898,683-88,913,411

MMP2

matrix metallopeptidase 2

4313

P08253

chr16: 55,389,700-55,506,691

MMP9

matrix metallopeptidase 9

4318

P14780

chr20: 46,008,908-46,016,561

MPO

myeloperoxidase

4353

P05164

chr17: 58,269,856-58,280,935

ATF3

activating transcription factor 3

467

P18847

chr1: 212,565,334-212,620,777

NOS3

nitric oxide synthase 3

4846

P29474

chr7: 150,990,995-151,014,588

ATP2A2

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

488

P16615

chr12: 110,280,756-110,351,093

SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

5054

P05121

chr7: 101,127,089-101,139,266

ACOX1

acyl-CoA oxidase 1, palmitoyl

51

Q15067

chr17: 75,941,507-75,979,363

PCK1

phosphoenolpyruvate carboxykinase 1

5105

P35558

chr20: 57,561,080-57,568,112

PDK4

pyruvate dehydrogenase kinase, isozyme 4

5166

Q16654

chr7: 95,583,499-95,596,491

PPARA

peroxisome proliferator-activated receptor alpha

5465

Q07869

chr22: 46,150,521-46,243,756

PPARG

peroxisome proliferator-activated receptor gamma

5468

P37231

chr3: 12,287,368-12,434,356

PRKCA

protein kinase C, alpha

5578

P17252

chr17: 66,302,636-66,810,743

PRKCD

protein kinase C, delta

5580

Q05655

chr3: 53,156,009-53,192,717

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

5743

P35354

chr1: 186,671,791-186,680,427

GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

57678

Q9HCL2

chr10: 112,149,864-112,215,377

BAX

BCL2-associated X protein

581

Q07812

chr19: 48,954,815-48,961,798

BCL2

B-cell CLL/lymphoma 2

596

P10415

chr18: 63,123,346-63,320,128

RELA

v-rel avian reticuloendotheliosis viral oncogene homolog A

5970

Q04206

chr11: 65,653,596-65,663,094

S100A6

S100 calcium binding protein A6

6277

P06703

chr1: 153,534,599-153,536,244

CCL20

chemokine (C-C motif) ligand 20

6364

P78556

chr2: 227,813,842-227,817,564

SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

6517

P14672

chr17: 7,281,667-7,288,257

SNAP25

synaptosome associated protein 25kDa

6616

P60880

chr20: 10,218,830-10,307,418

SOD2

superoxide dismutase 2, mitochondrial

6648

P04179

chr6: 159,669,057-159,762,529

SREBF1

sterol regulatory element binding transcription factor 1

6720

P36956

chr17: 17,810,399-17,837,002

TGFB1

transforming growth factor beta 1

7040

P01137

chr19: 41,301,587-41,353,911

TIMP1

TIMP metallopeptidase inhibitor 1

7076

P01033

chrX: 47,582,313-47,586,789

TIMP2

TIMP metallopeptidase inhibitor 2

7077

P16035

chr17: 78,852,977-78,925,387

TNF

tumor necrosis factor

7124

P01375

chr6: 31,575,567-31,578,336

TP53

tumor protein p53

7157

P04637

chr17: 7,661,779-7,687,550

UCP2

uncoupling protein 2 (mitochondrial, proton carrier)

7351

P55851

chr11: 73,974,667-73,983,307

VEGFA

vascular endothelial growth factor A

7422

P15692

chr6: 43,770,184-43,786,487

YWHAH

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

7533

Q04917

chr22: 31,944,461-31,957,603

CAV1

caveolin 1

857

Q03135

chr7: 116,524,785-116,561,184

AOC3

amine oxidase, copper containing 3

8639

Q16853

chr17: 42,851,184-42,858,130

AIFM1

apoptosis inducing factor, mitochondria associated 1

9131

O95831

chrX: 130,129,362-130,165,887

CD68

CD68 molecule

968

P34810

chr17: 7,579,467-7,582,113