Disease Description

UMLS CUI C0009375
UMLS Term Colonic Neoplasms
MeSH ID D003110
MeSH Term Colonic Neoplasms
Disease Classes

Neoplasms

Digestive System Diseases

Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

1026

P38936

chr6: 36,676,460-36,687,339

CRYAB

crystallin alpha B

1410

P02511

chr11: 111,908,565-111,923,722

CTNNB1

catenin beta 1

1499

P35222

chr3: 41,194,837-41,260,096

CYP26A1

cytochrome P450 family 26 subfamily A member 1

1592

O43174

chr10: 93,073,475-93,077,890

DMBT1

deleted in malignant brain tumors 1

1755

Q9UGM3

chr10: 122,560,665-122,643,736

DNMT1

DNA (cytosine-5-)-methyltransferase 1

1786

P26358

chr19: 10,133,345-10,231,286

DPYD

dihydropyrimidine dehydrogenase

1806

Q12882

chr1: 97,077,743-97,921,049

TYMP

thymidine phosphorylase

1890

P19971

chr22: 50,525,752-50,530,056

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

A2M

alpha-2-macroglobulin

2

P01023

chr12: 9,067,664-9,116,229

ERBB2

erb-b2 receptor tyrosine kinase 2

2064

P04626

chr17: 39,687,914-39,730,426

ALDH1B1

aldehyde dehydrogenase 1 family member B1

219

P30837

chr9: 38,392,664-38,398,661

FBP1

fructose-bisphosphatase 1

2203

P09467

chr9: 94,603,133-94,640,249

PLCB1

phospholipase C beta 1

23236

Q9NQ66

chr20: 8,077,251-8,968,360

FOLR1

folate receptor 1 (adult)

2348

P15328

chr11: 72,189,558-72,196,323

ALOX5

arachidonate 5-lipoxygenase

240

P09917

chr10: 45,374,176-45,446,119

GAP43

growth associated protein 43

2596

P17677

chr3: 115,623,324-115,721,490

GCG

glucagon

2641

P01275

chr2: 162,142,873-162,152,404

APC

adenomatous polyposis coli

324

P25054

chr5: 112,707,498-112,846,239

HES1

hes family bHLH transcription factor 1

3280

Q14469

chr3: 194,136,145-194,138,732

HSPB1

heat shock protein family B (small) member 1

3315

P04792

chr7: 76,302,544-76,304,295

BIRC5

baculoviral IAP repeat containing 5

332

O15392

chr17: 78,214,186-78,225,636

ICAM1

intercellular adhesion molecule 1

3383

P05362

chr19: 10,270,835-10,286,615

ID3

inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

3399

Q02535

chr1: 23,557,918-23,559,794

IGF2

insulin like growth factor 2

3481

P01344

chr11: 2,129,112-2,141,238

IGFBP1

insulin like growth factor binding protein 1

3484

P08833

chr7: 45,888,357-45,893,668

IL1B

interleukin 1 beta

3553

P01584

chr2: 112,829,751-112,836,903

IL1RN

interleukin 1 receptor antagonist

3557

P18510

chr2: 113,107,214-113,134,016

JUN

jun proto-oncogene

3725

P05412

chr1: 58,780,788-58,784,327

KCNH2

potassium channel, voltage gated eag related subfamily H, member 2

3757

Q12809

chr7: 150,944,961-150,978,315

KRAS

Kirsten rat sarcoma viral oncogene homolog

3845

P01116

chr12: 25,204,789-25,250,936

LEP

leptin

3952

P41159

chr7: 128,241,284-128,257,628

LPL

lipoprotein lipase

4023

P06858

chr8: 19,901,717-19,967,258

MAOB

monoamine oxidase B

4129

P27338

chrX: 43,766,611-43,882,447

MCM2

minichromosome maintenance complex component 2

4171

P49736

chr3: 127,598,223-127,622,436

MKI67

marker of proliferation Ki-67

4288

P46013

chr10: 128,096,659-128,126,385

MMP9

matrix metallopeptidase 9

4318

P14780

chr20: 46,008,908-46,016,561

MTHFR

methylenetetrahydrofolate reductase (NAD(P)H)

4524

P42898

chr1: 11,785,723-11,806,920

MYC

v-myc avian myelocytomatosis viral oncogene homolog

4609

P01106

chr8: 127,735,434-127,741,434

NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

4790

P19838

chr4: 102,501,329-102,617,302

NOTCH1

notch 1

4851

P46531

chr9: 136,494,444-136,545,862

ODC1

ornithine decarboxylase 1

4953

P11926

chr2: 10,439,968-10,448,504

NOX4

NADPH oxidase 4

50507

Q9NPH5

chr11: 89,324,356-89,498,187

PARK2

parkin RBR E3 ubiquitin protein ligase

5071

O60260

chr6: 161,347,420-162,727,771

PCNA

proliferating cell nuclear antigen

5111

P12004

chr20: 5,114,953-5,126,626

SERPINB5

serpin peptidase inhibitor, clade B (ovalbumin), member 5

5268

P36952

chr18: 63,476,761-63,505,085

PPARG

peroxisome proliferator-activated receptor gamma

5468

P37231

chr3: 12,287,368-12,434,356

XAF1

XIAP associated factor 1

54739

Q6GPH4

chr17: 6,755,447-6,775,647

MAP2K6

mitogen-activated protein kinase kinase 6

5608

P52564

chr17: 69,414,698-69,543,331

RHOJ

ras homolog family member J

57381

Q9H4E5

chr14: 63,204,114-63,293,219

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

5743

P35354

chr1: 186,671,791-186,680,427

NDRG2

NDRG family member 2

57447

Q9UN36

chr14: 21,016,763-21,070,872

BAX

BCL2-associated X protein

581

Q07812

chr19: 48,954,815-48,961,798

ACTA2

actin, alpha 2, smooth muscle, aorta

59

P62736

chr10: 88,935,074-88,991,339

BCL2

B-cell CLL/lymphoma 2

596

P10415

chr18: 63,123,346-63,320,128

RELA

v-rel avian reticuloendotheliosis viral oncogene homolog A

5970

Q04206

chr11: 65,653,596-65,663,094

S100A4

S100 calcium binding protein A4

6275

P26447

chr1: 153,543,613-153,550,136

S100A9

S100 calcium binding protein A9

6280

P06702

chr1: 153,357,854-153,361,027

CCL20

chemokine (C-C motif) ligand 20

6364

P78556

chr2: 227,813,842-227,817,564

SLC2A1

solute carrier family 2 (facilitated glucose transporter), member 1

6513

P11166

chr1: 42,925,375-42,959,173

SLC19A1

solute carrier family 19 (folate transporter), member 1

6573

P41440

chr21: 45,493,572-45,544,411

SLC22A1

solute carrier family 22 (organic cation transporter), member 1

6580

O15245

chr6: 160,121,789-160,158,718

SOD2

superoxide dismutase 2, mitochondrial

6648

P04179

chr6: 159,669,057-159,762,529

SPARC

secreted protein, acidic, cysteine-rich (osteonectin)

6678

P09486

chr5: 151,661,096-151,687,165

STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

6774

P40763

chr17: 42,313,324-42,388,568

TAGLN

transgelin

6876

Q01995

chr11: 117,199,321-117,204,782

TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

6934

Q9NQB0

chr10: 112,950,250-113,167,678

TCF19

transcription factor 19

6941

Q9Y242

chr6: 31,158,542-31,167,159

TGFBR2

transforming growth factor beta receptor II

7048

P37173

chr3: 30,606,502-30,694,142

TNF

tumor necrosis factor

7124

P01375

chr6: 31,575,567-31,578,336

TP53

tumor protein p53

7157

P04637

chr17: 7,661,779-7,687,550

TPM3

tropomyosin 3

7170

P06753

chr1: 154,155,304-154,194,648

ACTG2

actin, gamma 2, smooth muscle, enteric

72

P63267

chr2: 73,892,314-73,919,865

TYMS

thymidylate synthetase

7298

P04818

chr18: 657,604-673,578

UMPS

uridine monophosphate synthetase

7372

P11172

chr3: 124,730,366-124,749,273

VEGFA

vascular endothelial growth factor A

7422

P15692

chr6: 43,770,184-43,786,487

WT1

Wilms tumor 1

7490

P19544

chr11: 32,387,775-32,435,630

CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1

781

P54289

chr7: 81,946,444-82,443,798

RECK

reversion-inducing-cysteine-rich protein with kazal motifs

8434

O95980

chr9: 36,036,433-36,124,451

LGR5

leucine-rich repeat containing G protein-coupled receptor 5

8549

O75473

chr12: 71,439,770-71,586,310

CBR1

carbonyl reductase 1

873

P16152

chr21: 36,069,941-36,073,166

TNFSF10

tumor necrosis factor superfamily member 10

8743

P50591

chr3: 172,505,508-172,523,507

CCND2

cyclin D2

894

P30279

chr12: 4,273,772-4,305,350

IL32

interleukin 32

9235

P24001

chr16: 3,065,297-3,082,192